DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn77Ba and LOC299277

DIOPT Version :9

Sequence 1:	NP_001287128.1	Gene:	Spn77Ba / 40234	FlyBaseID:	FBgn0262057	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	XP_008763124.2	Gene:	LOC299277 / 299277	RGDID:	1595900	Length:	420	Species:	Rattus norvegicus

Alignment Length:	431	Identity:	107/431 - (24%)
Similarity:	189/431 - (43%)	Gaps:	47/431 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 LTAFTAPTAF--QSG-------VSHIQSMRSNFDTDVLVSISQGVQDFALDLLQRISVEVEKANK 96
            :||...|.|.  :.|       |...|..:...|:..|.||:   .|||..|.:.::  ::..||
  Rat    10 ITAVICPAALCCRDGTLGRHPEVQKDQDTKKQLDSGTLASIN---TDFAFSLYKELA--LKNPNK 69

  Fly    97 DFMISPFSVWSLLVLLYEGSEGETRNQLKKSLRINVEDE---KLRGAYKVWSSFLNITTSTIEVA 158
            :...||.|:.:.|..|..|::|.|..::.:.|:.|:.:.   .:...|:.....|:......:::
  Rat    70 NIAFSPLSISAALASLSLGAKGNTLQEILEGLKFNLTETTEIDIHQNYRDLLQRLSQPGGQGQIS 134

  Fly   159 TLQAIYTGKGYPIKNNYRD-AIQNYNVQPMEVDFYSPDSVIQ-INEDTNRTTRGLIPYTILPQDV 221
            ....::..|...|.|.::: |...|..:....||.......: ||:.....::|.|...:...:
  Rat   135 RANLLFVEKHLQILNGFKEKAKALYQTEVFATDFQQTCEARKFINDYVMIQSQGKIKEMVTELE- 198

  Fly   222 YGAKMFLLSSLYFKGQWKFPFNKTLTREEPFFSESGEVIGKIPMMVQEANFAYVSNVEGLDGYVL 286
            ....:.:|:.|.|.|||..||:...|....|..:|...:..:.|..::....|..: |.|...|:
  Rat   199 ERTSIVMLNFLLFTGQWSVPFDPDDTFMGKFILDSRRPVKVLMMKTEDLTTPYFWD-EELKCTVV 262

  Fly   287 ELPYGTQDRLAMIVVLPKRGFKLNDVANNLKALGLRPILQRLAAFRNRASEDNEVEVMMPKFVTA 351
            ||.|....: ||. :||.:| |:..|..:|....||.....|   :.|..:    |:.:|||..:
  Rat   263 ELNYKGHGK-AMF-ILPDQG-KMEQVEASLHPGTLRKWTDSL---KPRIID----ELHLPKFSLS 317

  Fly   352 TDFTLKGVLIQMGIRDLFDENT-ANLDRMSSGLFAKL--VVHSTKIIVDEQGTTAGAVTEAALAN 413
            ..:.|:.:|.::||.|:|  || |:|..::.....::  ::|:|.:.:.|.||.|.|.|.  :..
  Rat   318 KTYKLENILPELGIMDVF--NTQADLSGIAGAKDVRVSQMIHNTVLGMAETGTEAEATTR--VEY 378

  Fly   414 KATPPKFLLN-------RPFQYMIVEKATGLLLFAGQVRNP 447
            ...|.|  ||       |.|.||::|..:.|:.|..:|.||
  Rat   379 NFRPAK--LNDTFVNFVRKFLYMVLEPNSELISFMRKVINP 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Ba	NP_001287128.1	SERPIN	75..444	CDD:238101	93/383 (24%)
LOC299277	XP_008763124.2	serpinA3_A1AC	37..417	CDD:381019	98/402 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000