DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn77Ba and Serpina4

DIOPT Version :9

Sequence 1:	NP_001287128.1	Gene:	Spn77Ba / 40234	FlyBaseID:	FBgn0262057	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_659565.2	Gene:	Serpina4 / 246328	RGDID:	708581	Length:	423	Species:	Rattus norvegicus

Alignment Length:	467	Identity:	124/467 - (26%)
Similarity:	206/467 - (44%)	Gaps:	73/467 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 CLMLWIPLLLGAIFLCSADPQ-------NNQAPLQLSVGNPLTAFTAPTAFQSGVSHIQSMRSNF 64
            ||:|   ||.|.:.|..:.|.       .||...|.|              |..:|..|
  Rat     6 CLLL---LLAGLLELSHSQPDQEEPDNTTNQTYRQFS--------------QQNISSYQ------ 47

  Fly    65 DTDVLVSISQGVQDFALDLLQRISVEVEKANKDFMISPFSVWSLLVLLYEGSEGETRNQLKKSLR 129
                   |:.|..:||..|...|:  .:.:.|:...||.|:...|.:|..|:.|:|:.|:.:.|.
  Rat    48 -------IASGNANFAFRLYHLIA--SQNSEKNIFFSPLSISVSLAILSTGAGGDTQAQILEGLG 103

  Fly   130 INVEDEKLRGAYKVWSSFLN-----ITTSTIEVATLQAIYTGKGYPIKNNYRDAIQ-NYNVQPME 188
            .|:....|...::.:.|..:     .|...|.|.:  |:...:...|.:.:..||: :||.:.:.
  Rat   104 FNLTKLSLPEIHEGFRSLQHTIARPFTEPQISVGS--ALILSQNLQILSEFVSAIETSYNSKVLH 166

  Fly   189 VDFYSPDSVIQ-INEDTNRTTRGLIPYTI--LPQDVYGAKMFLLSSLYFKGQWKFPFNKTLTREE 250
            .:|...::.:| ||....:.|:|.|...:  |..||   ||.|::.::|:|.||.||..:.....
  Rat   167 ANFRDKEAAVQLINNYVKQNTQGKIKNLVSDLSPDV---KMVLVNYIFFQGLWKKPFPSSRVSTS 228

  Fly   251 PFFSESGEVIGKIPMMVQEANFAYVSNVEGLDGYVLELPYGTQDRLAMIVVLPKRGFKLNDVANN 315
            .|:.:...|: |||||:|:....:......:...||.:.| ..|.:|.. :||.:| |:|:|...
  Rat   229 DFYVDENTVV-KIPMMLQDKEDHWYLEDRRVPCTVLRMDY-RGDAVAFF-ILPDQG-KMNEVEQV 289

  Fly   316 LK---ALGLRPILQRLAAFRNRASEDNEVEVMMPKFVTATDFTLKGVLIQMGIRDLFDENTANLD 377
            |.   .|..:.:||....:|       ::.:.:|||..:..:.|..:|..:|.:|||..| ||..
  Rat   290 LSPGMLLRWKRLLQNRFFYR-------KLILQLPKFSISNSYELDEILPDLGFQDLFTPN-ANFS 346

  Fly   378 RMS--SGLFAKLVVHSTKIIVDEQGTTAGAVTEAALANKATPPK---FLLNRPFQYMIVEKATGL 437
            .:|  ..|:...|.|.|.:.|:|.||.|.|.|.:.....:..||   .:.||||..::...::..
  Rat   347 NISKKEKLYLSKVFHKTVLDVNEVGTKAAAATGSFATFFSAQPKKRYLIFNRPFLVILYSTSSQD 411

  Fly   438 LLFAGQVRNPKA 449
            :||.|:|.||.|
  Rat   412 ILFMGKVVNPTA 423

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Ba	NP_001287128.1	SERPIN	75..444	CDD:238101	104/385 (27%)
Serpina4	NP_659565.2	SERPIN	52..418	CDD:294093	103/384 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010