DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn77Ba and Serpine2

DIOPT Version :9

Sequence 1:	NP_001287128.1	Gene:	Spn77Ba / 40234	FlyBaseID:	FBgn0262057	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_033281.1	Gene:	Serpine2 / 20720	MGIID:	101780	Length:	397	Species:	Mus musculus

Alignment Length:	407	Identity:	110/407 - (27%)
Similarity:	202/407 - (49%)	Gaps:	40/407 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 IQSMRSNFDTDVLVSI--SQGVQDFALDLLQRISVEVEKANKDFMISPFSVWSLLVLLYEGSEGE 119
            :.|:.|.|::..|..:  :.|:|.|.       .:...:.:::.::||..:.|:|.:|..|::|:
Mouse    15 LYSVHSQFNSLSLEELGSNTGIQVFN-------QIIKSRPHENVVVSPHGIASILGMLQLGADGK 72

  Fly   120 TRNQLKKSLRINVEDEKLRGAYKVWSSFLN---ITTSTIEVATL-QAIYTGKGYPIKNNYRDAIQ 180
            |:.||...:|.||     .|..||... :|   ::....::.|: .|::...|:.::..:  |::
Mouse    73 TKKQLSTVMRYNV-----NGVGKVLKK-INKAIVSKKNKDIVTVANAVFLRNGFKMEVPF--AVR 129

  Fly   181 NYNV---QPMEVDFYSPDSVIQ-INEDTNRTTRGLIPYTILPQDVYGA--KMFLLSSLYFKGQWK 239
            |.:|   :...|:|..|.|..: ||......|||:|...:.|..:.||  ::.|::::||||.||
Mouse   130 NKDVFQCEVQNVNFQDPASASESINFWVKNETRGMIDNLLSPNLIDGALTRLVLVNAVYFKGLWK 194

  Fly   240 FPFNKTLTREEPFFSESGEVIGKIPMMVQEANFAYVS--NVEGLDGYVLELPYGTQDRLAMIVVL 302
            ..|....|::..|.:..|:.. ::||:.|.:.|...|  ...||....:||||..:. ::|::.|
Mouse   195 SRFQPESTKKRTFVAGDGKSY-QVPMLAQLSVFRSGSTRTPNGLWYNFIELPYHGES-ISMLIAL 257

  Fly   303 PKRGFKLNDVANNLKALGLRPILQRLAAFRNRASEDNEVEVMMPKFVTATDFTLKGVLIQMGIRD 367
            |      .:.:..|.|:......:.:.::.| ......:::::|||.......||..|..:||.:
Mouse   258 P------TESSTPLSAIIPHITTKTIDSWMN-TMVPKRMQLVLPKFTAVAQTDLKEPLKALGITE 315

  Fly   368 LFDENTANLDRM--SSGLFAKLVVHSTKIIVDEQGTTAGAVTEAALANKATPPKFLLNRPFQYMI 430
            :|:.:.||..::  |..|....::...||.|.|.||.|.|.|.|.|..:::||.|:::|||.:.|
Mouse   316 MFEPSKANFTKITRSESLHVSHILQKAKIEVSEDGTKASAATTAILIARSSPPWFIVDRPFLFSI 380

  Fly   431 VEKATGLLLFAGQVRNP 447
            ....||.:||.|||..|
Mouse   381 RHNPTGAILFLGQVNKP 397

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Ba	NP_001287128.1	SERPIN	75..444	CDD:238101	103/382 (27%)
Serpine2	NP_033281.1	serpinE2_GDN	21..395	CDD:381039	106/397 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.930