DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn77Ba and Serpina3n

DIOPT Version :9

Sequence 1:	NP_001287128.1	Gene:	Spn77Ba / 40234	FlyBaseID:	FBgn0262057	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_033278.2	Gene:	Serpina3n / 20716	MGIID:	105045	Length:	418	Species:	Mus musculus

Alignment Length:	402	Identity:	108/402 - (26%)
Similarity:	188/402 - (46%)	Gaps:	38/402 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 SNFDTDVLVSISQGVQDFALDLLQRISVEVEKANKDFMISPFSVWSLLVLLYEGSEGETRNQLKK 126
            :..|:..|.||:   .|||..|.:.:  .::..:|:.:.||.|:.:.|.::..|::|.|..::.:
Mouse    40 TQLDSLTLASIN---TDFAFSLYKEL--VLKNPDKNIVFSPLSISAALAVMSLGAKGNTLEEILE 99

  Fly   127 SLRINVEDEKLRGAYKVWSSF---LNITTSTIEVATLQAIYTGKGYPIKNNYRD-AIQNYNVQPM 187
            .|:.|:.:......::.:...   ||.....::::|..|::..|...|...::: |...|..:..
Mouse   100 GLKFNLTETSEADIHQGFGHLLQRLNQPKDQVQISTGSALFIEKRQQILTEFQEKARALYQAEAF 164

  Fly   188 EVDFYSPDSVIQ-INEDTNRTTRGLIPYTILPQDVYGAKMFLLSSLYFKGQWKFPFNKTLTREEP 251
            ..||..|....: ||:...:.|:|:|...:...| ....|.|::.:|||.:||.||:...|.:..
Mouse   165 TADFQQPRQAKKLINDYVRKQTQGMIKELVSDLD-KRTLMVLVNYIYFKAKWKVPFDPLDTFKSE 228

  Fly   252 FFSESGEVIGK-----IPMMVQEANFAYVSNVEGLDGYVLELPYGTQDRLAMIVVLPKRGFKLND 311
            |::      ||     :|||..|.........|.|...|:||.| |.:..||. :||.:| |:..
Mouse   229 FYA------GKRRPVIVPMMSMEDLTTPYFRDEELFCTVVELKY-TGNASAMF-ILPDQG-KMQQ 284

  Fly   312 VANNLKALGLRPILQRLAAFRNRASEDNEVEVMMPKFVTATDFTLKGVLIQMGIRDLFDENTANL 376
            |..:|:.       :.|..::|........|:.:|||..:||::|:.||.::|||::| ...|:|
Mouse   285 VEASLQP-------ETLRKWKNSLKPRMIDELHLPKFSISTDYSLEDVLSKLGIREVF-STQADL 341

  Fly   377 DRM--SSGLFAKLVVHSTKIIVDEQGTTAGAVTE---AALANKATPPKFLLNRPFQYMIVEKATG 436
            ..:  :..|....|||...:.|.|.||.|.|.|.   ..::.|..|.....||||..||.:..|.
Mouse   342 SAITGTKDLRVSQVVHKAVLDVAETGTEAAAATGVKFVPMSAKLYPLTVYFNRPFLIMIFDTETE 406

  Fly   437 LLLFAGQVRNPK 448
            :..|..::.|||
Mouse   407 IAPFIAKIANPK 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Ba	NP_001287128.1	SERPIN	75..444	CDD:238101	101/383 (26%)
Serpina3n	NP_033278.2	serpinA3_A1AC	37..418	CDD:381019	106/400 (27%)
Serpina3n	NP_033278.2	RCL	367..392		7/24 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910