DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Spn77Ba and Serpina3k

DIOPT Version :9

Sequence 1:	NP_001287128.1	Gene:	Spn77Ba / 40234	FlyBaseID:	FBgn0262057	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_035588.2	Gene:	Serpina3k / 20714	MGIID:	98377	Length:	418	Species:	Mus musculus

Alignment Length:	432	Identity:	116/432 - (26%)
Similarity:	201/432 - (46%)	Gaps:	36/432 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 LSVGNPLTAFTAPT--AFQSGVSHI-------QSMRSNFDTDVLVSISQGVQDFALDLLQRISVE 90
            :::|..|.|...|.  .|..|...:       |...:..|:..|.|::   .|||..|.::::
Mouse     5 VAMGMILMAGICPAVLCFPDGTKEMDIVFHEHQDNGTQDDSLTLASVN---TDFAFSLYKKLA-- 64

  Fly    91 VEKANKDFMISPFSVWSLLVLLYEGSEGETRNQLKKSLRINVEDEKLRGAYKVWSSFLNITTSTI 155
            ::..:|:.:.||.|:.:.|.|:..|::|:|..::.:.|:.|:.:......::.:.:.|...:...
Mouse    65 LKNQDKNIVFSPLSISAALALVSLGAKGKTMEEILEGLKFNLTETPEADIHQGFGNLLQSLSQPE 129

  Fly   156 EVATL---QAIYTGKGYPIKNNYRDAIQN-YNVQPMEVDFYSP-DSVIQINEDTNRTTRGLIPYT 215
            :...:   .|::..|...|...:.:..:. |..:....||..| ::...||:..:..|:|:|...
Mouse   130 DQDQINIGNAMFIEKDLQILAEFHEKTRALYQTEAFTADFQQPTEAKNLINDYVSNQTQGMIKKL 194

  Fly   216 ILPQDVYGAKMFLLSSLYFKGQWKFPFNKTLTREEPFFSESGEVIGKIPMMVQEANFAYVSNVEG 280
            |...| .|..|.|::.:||||:||..|:...|.|..|:.:....: |:|||..:...|.....|.
Mouse   195 ISELD-DGTLMVLVNYIYFKGKWKISFDPQDTFESEFYLDEKRSV-KVPMMKMKLLTARHFRDEE 257

  Fly   281 LDGYVLELPYGTQDRLAMIVVLPKRGFKLNDVANNLKALGLRPILQRLAAFRNRASEDNEVEVMM 345
            |...||||.|  ....:.:::||.:| ::..|..:|:...||.  .|...|.::..|.|     :
Mouse   258 LSCSVLELKY--TGNASALLILPDQG-RMQQVEASLQPETLRK--WRKTLFSSQIEELN-----L 312

  Fly   346 PKFVTATDFTL-KGVLIQMGIRDLFDENTANLDRMSSG--LFAKLVVHSTKIIVDEQGTTAGAVT 407
            |||..|:|:.| :.||.:|||:::|.|. |:|..::..  |....|||...:.|.|.||.|.|.|
Mouse   313 PKFSIASDYRLEEDVLPEMGIKEVFTEQ-ADLSGITEAKKLSVSQVVHKAVLDVAETGTEAAAAT 376

  Fly   408 EA-ALANKATPPKFLLNRPFQYMIVEKATGLLLFAGQVRNPK 448
            .. ....||..|....||||..:|...:...:||..:|.|||
Mouse   377 GVIGGIRKAVLPAVCFNRPFLIVIYHTSAQSILFMAKVNNPK 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Ba	NP_001287128.1	SERPIN	75..444	CDD:238101	102/377 (27%)
Serpina3k	NP_035588.2	SERPIN	57..417	CDD:214513	100/374 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.000