DRSC/TRiP Functional Genomics Resources

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Protein Alignment Spn77Ba and Serpina1c

DIOPT Version :10

Sequence 1:NP_649205.3 Gene:Spn77Ba / 40234 FlyBaseID:FBgn0262057 Length:450 Species:Drosophila melanogaster
Sequence 2:NP_033271.1 Gene:Serpina1c / 20702 MGIID:891969 Length:413 Species:Mus musculus


Alignment Length:420 Identity:107/420 - (25%)
Similarity:183/420 - (43%) Gaps:69/420 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly    51 QSGVSHIQSMRSNFDTDVLVSISQGVQDFALDLLQRISVEVEKAN-KDFMISPFSVWSLLVLLYE 114
            ||..||              .|:..:.|||:.|.:.:   |.::| .:...||.|:.:...:|..
Mouse    37 QSPASH--------------EIATNLGDFAISLYREL---VHQSNTSNIFFSPVSIATAFAMLSL 84

  Fly   115 GSEGETRNQLKKSLRINVEDEKLRGAYKVWSSF---LNITTSTIEVATLQAIYTGKGYPIKNNYR 176
            ||:|:|..|:.:.|:.|:........:|.:...   ||...|.::::      ||.|..:.|:.:
Mouse    85 GSKGDTHTQILEGLQFNLTQTSEADIHKSFQHLLQTLNRPDSELQLS------TGNGLFVNNDLK 143

  Fly   177 -------DAIQNYNVQPMEVDF-YSPDSVIQINEDTNRTTRGLIPYTI--LPQDVYGAKMFLLSS 231
                   :|..:|..:...|:| .|.::...||:...:.|:|.|...:  |.||...|   |.:.
Mouse   144 LVEKFLEEAKNHYQAEVFSVNFAESEEAKKVINDFVEKGTQGKIAEAVKKLDQDTVFA---LANY 205

  Fly   232 LYFKGQWKFPFNKTLTREEPFFSESGEVIGKIPMMVQEANFAYVSNVEGLDGYVLELPYGTQDRL 296
            :.|||:||.||:...|.|..|..:....: |:|||.. :....|.:...|..:||.:.|.  ...
Mouse   206 ILFKGKWKKPFDPENTEEAEFHVDESTTV-KVPMMTL-SGMLDVHHCSTLSSWVLLMDYA--GNA 266

  Fly   297 AMIVVLPKRGFKLNDVANNL------KALGLRPILQRLAAFRNRASEDNEVEVMMPKFVTATDFT 355
            ..:.:||..| |:..:...|      |.|..||  :|||            ::..|:...:.::.
Mouse   267 TAVFLLPDDG-KMQHLEQTLSKELISKFLLKRP--RRLA------------QIHFPRLSISGEYN 316

  Fly   356 LKGVLIQMGIRDLFDENTANLDRM---SSGLFAKLVVHSTKIIVDEQGTTAGAVTEAALANKATP 417
            ||.::..:||..:|: |.|:|..:   ::.|.....||...:.:||.||.|.|.|.......:.|
Mouse   317 LKTLMSPLGITRIFN-NGADLSGITEENAPLKLSQAVHKAVLTMDETGTEAAAATVLLAVPYSMP 380

  Fly   418 PKFLLNRPFQYMIVEKATGLLLFAGQVRNP 447
            |....:.||.::|.|:.|...||.|:|.:|
Mouse   381 PIVRFDHPFLFIIFEEHTQSPLFVGKVVDP 410

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Spn77BaNP_649205.3 serpin77Ba-like_insects 72..447 CDD:381062 102/397 (26%)
Serpina1cNP_033271.1 serpinA1_A1AT 44..412 CDD:381012 103/399 (26%)

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