Protein Alignment Spn77Ba and Serpina1a

DIOPT Version :10

• Sequence 1: NP_649205.3
• Gene: Spn77Ba / 40234
• FlyBaseID: FBgn0262057
• Length: 450
• Species: Drosophila melanogaster
• Sequence 2: NP_001239498.1
• Gene: Serpina1a / 20700
• MGIID: 891971
• Length: 436
• Species: Mus musculus
• Alignment Length: 415
• Identity: 106/415 - (25%)
• Similarity: 187/415 - (45%)
• Gaps: 59/415 - (14%)

  Fly    51 QSGVSHIQSMRSNFDTDVLVSISQGVQDFALDLLQRISVEVEKAN-KDFMISPFSVWSLLVLLYE 114
            ||..||              .|:..:.|||:.|.:.:   |.::| .:...||.|:.:...:|..
Mouse    60 QSPASH--------------EIATNLGDFAISLYREL---VHQSNTSNIFFSPVSIATAFAMLSL 107

  Fly   115 GSEGETRNQLKKSLRINVEDEKLRGAYKVWSSF---LNITTSTIEVATLQAIYTGKGYPIKNNYR 176
            ||:|:|..|:.:.|:.|:........:|.:...   ||...|.::::      ||.|..:.|:.:
Mouse   108 GSKGDTHTQILEGLQFNLTQTSEADIHKSFQHLLQTLNRPDSELQLS------TGNGLFVNNDLK 166

  Fly   177 -------DAIQNYNVQPMEVDF-YSPDSVIQINEDTNRTTRGLIPYTI--LPQDVYGAKMFLLSS 231
                   :|..:|..:...|:| .|.::...||:...:.|:|.|...:  |.||...|   |.:.
Mouse   167 LVEKFLEEAKNHYQAEVFSVNFAESEEAKKVINDFVEKGTQGKIAEAVKKLDQDTVFA---LANY 228

  Fly   232 LYFKGQWKFPFNKTLTREEPFFSESGEVIGKIPMMVQEANFAYVSNVEGLDGYVLELPYGTQDRL 296
            :.|||:||.||:...|.|..|..:....: |:|||.. :...:|.:...|..:||.:.|.  ...
Mouse   229 ILFKGKWKKPFDPENTEEAEFHVDESTTV-KVPMMTL-SGMLHVHHCSTLSSWVLLMDYA--GNA 289

  Fly   297 AMIVVLPKRGFKLNDVANNL-KALGLRPILQRLAAFRNRASEDNEVEVMMPKFVTATDFTLKGVL 360
            ..:.:||..| |:..:...| |.|..:.:|.|    |.|.:     ::..|:...:.::.||.::
Mouse   290 TAVFLLPDDG-KMQHLEQTLSKELISKFLLNR----RRRLA-----QIHFPRLSISGEYNLKTLM 344

  Fly   361 IQMGIRDLFDENTANLDRM---SSGLFAKLVVHSTKIIVDEQGTTAGAVTEAALANKATPPKFLL 422
            ..:||..:|: |.|:|..:   ::.|.....||...:.:||.||.|.|||...:...:.||....
Mouse   345 SPLGITRIFN-NGADLSGITEENAPLKLSQAVHKAVLTIDETGTEAAAVTVLQMVPMSMPPILRF 408

  Fly   423 NRPFQYMIVEKATGLLLFAGQVRNP 447
            :.||.::|.|:.|...:|.|:|.:|
Mouse   409 DHPFLFIIFEEHTQSPIFLGKVVDP 433

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Ba	NP_649205.3	serpin77Ba-like_insects	72..447	CDD:381062	101/392 (26%)
Serpina1a	NP_001239498.1	serpinA1_A1AT	67..435	CDD:381012	102/394 (26%)