DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn77Ba and srp-7

DIOPT Version :9

Sequence 1:	NP_001287128.1	Gene:	Spn77Ba / 40234	FlyBaseID:	FBgn0262057	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_001122924.1	Gene:	srp-7 / 179195	WormBaseID:	WBGene00005648	Length:	373	Species:	Caenorhabditis elegans

Alignment Length:	380	Identity:	102/380 - (26%)
Similarity:	175/380 - (46%)	Gaps:	55/380 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 QGVQDFALDLLQRISVEVEKANKDFMISPFSVWSLLVLLYEGSEGETRNQLKKSLRINVEDEKLR 138
            |...||.|.||::     :..::....||.|:...|.|::..::||||:|::::|.....||:|.
Worm    13 QSETDFGLGLLRQ-----QNISESLAFSPLSIALALSLVHVAAKGETRDQIREALVKGSTDEQLE 72

  Fly   139 GAYKVWSSFLNITTSTI------EVATLQAIYTGKGYPIKNNYRDAIQN-YNVQPMEVDFYSPDS 196
                  ..|.||:.:.:      ||.....::|..|:.||.:|.|.::. ||.....:||.:.::
Worm    73 ------QHFANISAALLAAERGTEVKLANHVFTRAGFKIKQSYLDDVKKLYNAGASSLDFDNKEA 131

  Fly   197 VIQ-----INEDTNRTTRGLIPYTILPQDVYGAKMFLLSSLYFKGQWKFPFNKTLTREEPFFSES 256
            ..:     :.|:|....:.:|....:..|:...   |.::||||..|:..|.|..|.:..|||.:
Worm   132 TAEAINNFVRENTGDHIKKIIGSDSINSDLVAV---LTNALYFKADWQNKFKKDSTFKSEFFSSA 193

  Fly   257 GEVIGKIPMMVQEANFAYVSNV-----EGLDGYVLELPYGTQDRLAMIVVLPKRGFKLNDVANNL 316
            ..        .:|.:|.:.|:|     |.....||.||| ..:..|:.:.|||..|.|.:....|
Worm   194 DS--------KREIDFLHASSVSRDYAENDQFQVLSLPY-KDNTFALTIFLPKTRFGLTESLKTL 249

  Fly   317 KALGLRPILQRLAAFRNRASEDNEVEVMMPKFVTATDFTLKGVLIQMGIRDLFDENTANLDRMSS 381
            .:..::.:|..:::        ..|.|.:||:...|...|:..|..:||:..|| |.|:|..|:.
Worm   250 DSATIQHLLSNVSS--------TSVNVQIPKWKIETKLGLEEALQSLGIKKAFD-NDADLGNMAD 305

  Fly   382 GLFAKLVVHSTKIIVDEQGTTAGAVTEAALANKAT------PPKFLLNRPFQYMI 430
            ||:...|.|...|.|||:||.|.|.|..:::.|:.      |..|..:.||.:::
Worm   306 GLYVSKVTHKALIEVDEEGTKAAAATTVSISLKSAMFVMEEPKDFTADHPFFFVL 360

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Ba	NP_001287128.1	SERPIN	75..444	CDD:238101	101/379 (27%)
srp-7	NP_001122924.1	serpinL_nematode	14..372	CDD:381047	101/379 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.930