DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn77Ba and Serpini2

DIOPT Version :9

Sequence 1:	NP_001287128.1	Gene:	Spn77Ba / 40234	FlyBaseID:	FBgn0262057	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_001127881.1	Gene:	Serpini2 / 171149	RGDID:	619897	Length:	405	Species:	Rattus norvegicus

Alignment Length:	393	Identity:	100/393 - (25%)
Similarity:	180/393 - (45%)	Gaps:	37/393 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 SISQGVQDFALDLLQRISVEVEKANKDFMI-SPFSVWSLLVLLYEGSEGETRNQLKKSLRINVED 134
            ::.|...:||:||.:.||:    :||:.:| ||.....||.::..|::|:.:.|:.::||  ::.
  Rat    21 TMDQKNAEFAVDLYKAISL----SNKNNVIFSPLGTTVLLGMVQLGAKGKAQQQIMQTLR--MQK 79

  Fly   135 EKLRGAYKVWSSFLNITTS-----TIEVATLQAIYTGKGYPIKNNYRDAIQNYNVQPME-VDFYS 193
            ......:.|..|..:..:.     |..:|:  |:|..:|:.:|.:|..:.:.:.....: |||..
  Rat    80 TSTGEEFSVLKSLFSAISKKKQEFTFNLAS--ALYLQEGFIVKESYLHSNKEFFQSATKLVDFLD 142

  Fly   194 PDSVIQ-INEDTNRTTRGLIPYTILPQDVYG--AKMFLLSSLYFKGQWKFPFNKTLTREEPFFSE 255
            ..:..| |:......|.|.|......:| :|  .::.|::::||||.||..|.|..|....|..:
  Rat   143 AKTSAQAISTWVESKTDGKIKNMFSEED-FGPLTRLVLVNAIYFKGDWKQKFRKEDTEMTDFSKK 206

  Fly   256 SGEVIGKIPMM--VQEANFAYVSNVEGLDGYVLELPYGTQDRLAMIVVLPKRGFKLNDVANNLKA 318
            .|..: |||||  :..|.:.|.|. ..:...|||||| ..|..:::::||.....:.:|...:.|
  Rat   207 DGSTV-KIPMMKALLRAKYGYFSE-SSMTYQVLELPY-KADEFSLVILLPTEDVNIEEVEKQVTA 268

  Fly   319 LGLRPILQRLAAFRNRASEDNEVEVMMPKFVTATDFTLKGVLIQMGIRDLFDENTANLDRM--SS 381
            ..::.....|        .:.||||.:|:|........|..|..:.:.::| ....:|..:  ||
  Rat   269 RHVQKWFSEL--------HEEEVEVSLPRFKIEQKLDFKEALFSLNVTEIF-SGGCDLSGITDSS 324

  Fly   382 GLFAKLVVHSTKIIVDEQGTTAGAVT--EAALANKATPPKFLLNRPFQYMIVEKATGLLLFAGQV 444
            .|:....:......::|.|:.|.|.|  ........|..:||.|.||.:::....|..:||.|:|
  Rat   325 ELYVSRAMQKVFFEINEDGSEAAASTGINIPAIMSLTQTQFLANHPFLFIMKHIQTESILFMGKV 389

  Fly   445 RNP 447
            .:|
  Rat   390 TDP 392

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Ba	NP_001287128.1	SERPIN	75..444	CDD:238101	97/384 (25%)
Serpini2	NP_001127881.1	SERPIN	23..405	CDD:294093	100/391 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.930