DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn77Ba and LOC110439158

DIOPT Version :9

Sequence 1:	NP_001287128.1	Gene:	Spn77Ba / 40234	FlyBaseID:	FBgn0262057	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	XP_021329696.1	Gene:	LOC110439158 / 110439158	-ID:	-	Length:	412	Species:	Danio rerio

Alignment Length:	453	Identity:	123/453 - (27%)
Similarity:	193/453 - (42%)	Gaps:	65/453 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LMLWIPLLLG-AIFLCSADPQNNQAPLQLSVGNPLTAFTAPTAFQSGVSHIQSMRSNFDTDVLVS 71
            :.|||   .| ||.:|     .||..||    .|..:...|:                    |::
Zfish     6 VFLWI---CGFAIVVC-----GNQETLQ----QPPISAKLPS--------------------LIN 38

  Fly    72 ISQGVQDFALDLLQRISVEVEKANKDFMISPFSVWSLLVLLYEGSEGETRNQLKKSLRINVEDEK 136
            |:   .|||..|.:|:....:..:|:...|||:|...|..|..|:.|:|:.||...:..|.....
Zfish    39 IN---NDFAFHLYKRLIESPDYQSKNIFFSPFTVSMALSKLTLGAGGDTKQQLLSGIGYNSAIFS 100

  Fly   137 LRGAYKVWSSFL----NITTSTIEVATLQAIYTGKGY-PIKNNYRDAIQNYNVQPMEVDFYSPDS 196
            ....::::.|.|    |.|...|::.|  |:|....: |......|..:.|:.....|||...::
Zfish   101 TEEMHQLFHSLLEDIGNRTGVDIDIGT--ALYASDRFKPHSKFLEDMKEFYHTDGFTVDFRVKET 163

  Fly   197 VIQINEDTNRTTRGLIPYTI--LPQDVYGAKMFLLSSLYFKGQWKFPFNKTLTREEPFFSESGEV 259
            |.|||:.....|.|.|...:  |.:|..   ||||:.:||||:|..|||...|.|..|..:....
Zfish   164 VDQINKYVEEKTHGKINQAVDDLEKDTL---MFLLTYIYFKGKWDKPFNPEKTCESTFHIDDKTT 225

  Fly   260 IGKIPMMVQEANFAYVSNVEGLDGYVLELPYGTQDRLAMIVVLPKRGFKLNDV---ANNLKALGL 321
            : .:.||.|........:.| |...||.|.|  .|..:|.:.:|       ||   ...::.|.:
Zfish   226 V-PVQMMHQYEYLKVYYDAE-LSIKVLCLDY--NDSFSMFLAVP-------DVHMGRKTIEDLEM 279

  Fly   322 RPILQRLAAFRNRASEDNEVEVMMPKFVTATDFTLKGVLIQMGIRDLFDENTANLDRMSSGLFAK 386
            ....|.:..:: |::.:.:|::.:||....|.:.|..:|..||:.|:|.:...........:|..
Zfish   280 TISRQHIEKWK-RSAFERKVDIYVPKLSLKTSYFLNDILKGMGMADMFSDKADFTGVSEEKIFIS 343

  Fly   387 LVVHSTKIIVDEQGTTAGAVTEAALANKATPPKFLL--NRPFQYMIVEKATGLLLFAGQVRNP 447
            .|||...:.:||:||||.|||.......:..|...|  :|||...|.::....:||.|:|.||
Zfish   344 KVVHKATLDIDEKGTTAAAVTTVQFRQLSYSPLSTLSFDRPFMIFITDQTNDNILFFGKVVNP 406

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Ba	NP_001287128.1	SERPIN	75..444	CDD:238101	105/380 (28%)
LOC110439158	XP_021329696.1	alpha-1-antitrypsin_like	40..403	CDD:239011	105/382 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920