DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn77Ba and LOC100909605

DIOPT Version :9

Sequence 1:	NP_001287128.1	Gene:	Spn77Ba / 40234	FlyBaseID:	FBgn0262057	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	XP_006240581.2	Gene:	LOC100909605 / 100909605	RGDID:	6502633	Length:	410	Species:	Rattus norvegicus

Alignment Length:	416	Identity:	120/416 - (28%)
Similarity:	198/416 - (47%)	Gaps:	42/416 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 TAFQSGVSHIQSMRSNFDTDVLVSISQGVQDFALDLLQRISVEVEKANKDFMISPFSVWSLLVLL 112
            ||.|.|    |..:...|:..|.|.:   .|||..|.:.:  .::..:|:.:.|.||:.:.||||
  Rat    20 TAVQKG----QDNKIQVDSSTLSSCN---TDFAFSLYKEL--VLKNPDKNIVFSSFSISTALVLL 75

  Fly   113 YEGSEGETRNQLKKSLRINV---EDEKLRGAYKVWSSFLNITTSTIEVATLQAIYTGKGYPIKNN 174
            ..|::..|..::.:.|:.|:   .:.::...|:.....||:....::::|..|::..|...|...
  Rat    76 SLGAKNNTLKEILEGLKFNLTETPEAEIHQGYEHLLQRLNLPGDQVQISTGSALFIKKHLQILAE 140

  Fly   175 YRD-AIQNYNVQPMEVDFYSPDSVIQ-INEDTNRTTRGLIPYTILPQDVYGAKMFLLSSLYFKGQ 237
            ::: |...|..:....||..|....: ||:...:.|:|.|...|...| ....|.|::.:||||:
  Rat   141 FQEKARALYQAEAFSTDFQQPHEAKKLINDYVRKQTQGKIKELISVLD-KKTSMVLVNYIYFKGK 204

  Fly   238 WKFPFNKTLTREEPFFSESGEVIGKIPMM-VQEANFAYVSNVEGLDGYVLELPYGTQDRLAMIVV 301
            ||.||:...|.:..|:.:..:.: |:||| :::....|..: |.|...||||.|  ....:.:.:
  Rat   205 WKMPFDPHDTFQSEFYLDEKKSV-KVPMMKIEKLTTPYFRD-EELSCSVLELKY--TGNASALFI 265

  Fly   302 LPKRGFKLNDVANNLKALGLRPILQRLAAFRNRASEDNEVEVMMPKFVTATDFTLKGVLIQMGIR 366
            ||.:| ::..|..:|:...||.....|   |.|..:    |:.||||..:||..|..:|.::|||
  Rat   266 LPDQG-RMQQVEASLQPETLRRWKDTL---RPRRID----ELRMPKFSISTDMRLGDILPELGIR 322

  Fly   367 DLFDENTANLDRMSSG--LFAKLVVHSTKIIVDEQGTTAGAVTEAALANKATP--PKF-----LL 422
            ::|.:. |:|.|::..  |....|||...:.|.|.||.|.|.|..    |..|  .||     ..
  Rat   323 EVFSQQ-ADLSRITGAKDLSVSQVVHKAVLDVTETGTEAAAATGV----KIIPMCAKFYYVTMYF 382

  Fly   423 NRPFQYMIVEKATGLLLFAGQVRNPK 448
            ||||..:|.:..|.:.||..:|.|||
  Rat   383 NRPFLMIISDTNTHIALFMAKVTNPK 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Ba	NP_001287128.1	SERPIN	75..444	CDD:238101	108/383 (28%)
LOC100909605	XP_006240581.2	alpha-1-antitrypsin_like	41..404	CDD:239011	108/385 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910