DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn77Ba and serpina10b

DIOPT Version :9

Sequence 1:	NP_001287128.1	Gene:	Spn77Ba / 40234	FlyBaseID:	FBgn0262057	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	XP_009291625.1	Gene:	serpina10b / 100003661	ZFINID:	ZDB-GENE-100716-5	Length:	395	Species:	Danio rerio

Alignment Length:	450	Identity:	111/450 - (24%)
Similarity:	210/450 - (46%)	Gaps:	81/450 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LLLGAIFLCSADPQNNQAPLQLSVGNPLTAFTAPTAFQSGVSHIQSMRSNFDTDVLVSISQGVQD 78
            :.:.|.|||||:.:..:.|           ..:..||::                        .|
Zfish     8 VFISACFLCSAEHEELRTP-----------DISDLAFRN------------------------TD 37

  Fly    79 FALDLLQRISVEVEKANKDFMISPFSVWSLLVLLYEGSEGETRNQLKKSLRINVEDEKLRG--AY 141
            ||::|.::||   ...:::.:.||.||.:....|...::|.||.::.|.|.:    |.|.|  :.
Zfish    38 FAINLYRKIS---SLHDRNVVFSPLSVSTCFSALLLAAQGSTRTEILKGLNL----EALDGGDSR 95

  Fly   142 KVWSSFLNITTS-TIEVATLQAIYTGKGYPIKNNYRDAIQN-YNVQPMEVDFYSPDSVIQ--INE 202
            :|...|..:..: ::::....|::..:.:.::.|:...||. :|.:.:.|||..| :|.:  |||
Zfish    96 RVPELFQQLHQNISLQMEQGTALFLDQHFHLQTNFSQQIQRFFNAEVLRVDFSKP-AVCRSLINE 159

  Fly   203 DTNRTT--------RGLIPYTILPQDVYGAKMFLLSSLYFKGQWKFPFNKTLTREEPFFSESGEV 259
            ..:|.|        ..:.|.|         :|.||:::::||.|:.|||...|.:..|:.:...:
Zfish   160 FVSRKTGRKVLEMLESVEPLT---------QMLLLNTIFYKGDWERPFNPNNTEKSRFYVDKYNI 215

  Fly   260 IGKIPMMVQEANFAYVSNVEGLDGYVLELPYGTQDRLAMIVVLPKRGFKLNDVANNLKALGLRPI 324
            : ::|||:.|..|:.|.: ..|...||.|||  :...:|:::||........:.:.:.|..|...
Zfish   216 V-QVPMMMLEEKFSVVED-RDLRARVLRLPY--RGGASMLILLPSADADYTAIEDEISAERLHGW 276

  Fly   325 LQRLAAFRNRASEDNEVEVMMPKFVTATDFTLKGVLIQMGIRDLFDENTANLDRMSSGLFAKL-- 387
            ::.:...:        :||.:|:|.....:.:..:|.|:||..:| :::|:|..:|.....|:
Zfish   277 IKNMRRMK--------MEVHLPRFRMDQSYHMHELLPQLGISSVF-QDSADLTGLSRDAHLKVSQ 332

  Fly   388 VVHSTKIIVDEQGTTAGAVTEAALANKATPPKFLLNRPFQYMIVEKATGLLLFAGQVRNP 447
            |:|...|.|.||||:|.:.|...:...:.|..|::||||.:.:..:.|..|||.|:|.:|
Zfish   333 VLHKAVIEVYEQGTSAASSTSVGITAYSLPDTFIINRPFFFFLYHEETASLLFMGRVIDP 392

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn77Ba	NP_001287128.1	SERPIN	75..444	CDD:238101	100/384 (26%)
serpina10b	XP_009291625.1	Serpin	35..392	CDD:278507	101/410 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.010