Protein Alignment polo and polo

DIOPT Version :10

• Sequence 1: NP_524179.2
• Gene: polo / 40232
• FlyBaseID: FBgn0003124
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: XP_313155.3
• Gene: polo / 1274084
• VectorBaseID: AGAMI1_011846
• Length: 575
• Species: Anopheles gambiae
• Alignment Length: 574
• Identity: 411/574 - (71%)
• Similarity: 484/574 - (84%)
• Gaps: 6/574 - (1%)

  Fly     3 AKPEDKSTDIPDRLVDINQRKTYKRMRFFGKGGFAKCYEIIDVETDDVFAGKIVSKKLMIKHNQK 67
            |||::|:.|||::|.|...::||:||||||||||||||||:||.|::||||||||||||:|||||
Mosquito     5 AKPDEKAVDIPEKLYDAGTKRTYRRMRFFGKGGFAKCYEIVDVATNEVFAGKIVSKKLMMKHNQK 69

  Fly    68 EKTAQEITIHRSLNHPNIVKFHNYFEDSQNIYIVLELCKKRSMMELHKRRKSITEFECRYYIYQI 132
            ||..|||||||||||.|||.||::|:|..||||||||||||||||||||||.||::|||||::|:
Mosquito    70 EKMTQEITIHRSLNHKNIVGFHSFFDDPLNIYIVLELCKKRSMMELHKRRKIITDYECRYYMHQV 134

  Fly   133 IQGVKYLHDNRIIHRDLKLGNLFLNDLLHVKIGDFGLATRIEYEGERKKTLCGTPNYIAPEILTK 197
            :.|||||||..|||||||||||||||.||||||||||||:||::|||||||||||||||||||.|
Mosquito   135 MTGVKYLHDKHIIHRDLKLGNLFLNDELHVKIGDFGLATKIEFDGERKKTLCGTPNYIAPEILNK 199

  Fly   198 KGHSFEVDIWSIGCVMYTLLVGQPPFETKTLKDTYSKIKKCEYRVPSYLRKPAADMVIAMLQPNP 262
            ||||:||||||||||||||||||||||||:|||||::|:||:||:|..||..||:|:.||||.:|
Mosquito   200 KGHSYEVDIWSIGCVMYTLLVGQPPFETKSLKDTYNRIRKCDYRLPPTLRNTAAEMICAMLQSDP 264

  Fly   263 ESRPAIGQLLNFEFLKGSKVPMFLPSSCLTMAPRIGSNDTIE--DSMHRKPLMEMNGIRPDDTRL 325
            ..||.|.:|..||||.||.:|..||.||||||||.   |.:|  :.|:||||.|||| ..|:||.
Mosquito   265 MKRPRIHKLFEFEFLSGSHIPNSLPISCLTMAPRA---DQLEQAERMNRKPLSEMNG-AGDETRF 325

  Fly   326 ESTFLKANLHDAITASAQVCRHSEDYRSDIESLYQQLTNLINGKPRILQGNLGDENTDPAAQPLF 390
            ||:|||.||||.||||..:.||::.||:|||:|:::||.|...||..|..||.|||||||.||||
Mosquito   326 ESSFLKNNLHDPITASGMISRHNDTYRADIETLHRELTKLFLAKPARLASNLDDENTDPAVQPLF 390

  Fly   391 WISKWVDYSDKYGFGYQLCDEGIGVMFNDTTKLILLPNQINVHFIDKDGKETYMTTTDYCKSLDK 455
            |:||||||||||||||||.|||:|||||||||||:|.|..|||||||:|:|:|.....:...|:|
Mosquito   391 WVSKWVDYSDKYGFGYQLSDEGMGVMFNDTTKLIMLANGHNVHFIDKEGQESYWDVNSFPPYLEK 455

  Fly   456 KMKLLSYFKRYMIEHLVKAGANNVNIESDQISRMPHLHSWFRTTCAVVMHLTNGSVQLNFSDHMK 520
            |||||:||||||:||||||||..:|:|||||||:||:|:||||.||||||||||:||||||||.|
Mosquito   456 KMKLLTYFKRYMMEHLVKAGAGVMNVESDQISRIPHMHTWFRTMCAVVMHLTNGTVQLNFSDHQK 520

  Fly   521 LILCPRMSAITYMDQEKNFRTYRFSTIVENGVSKDLYQKIRYAQEKLRKMLEKM 574
            :||||.|.|:|.||..||||||||.||:|:|.|.|||.|||||.||::|:|||:
Mosquito   521 IILCPLMRAVTLMDNNKNFRTYRFQTIIEHGCSHDLYTKIRYAHEKIKKLLEKL 574

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
polo	NP_524179.2	STKc_PLK	23..277	CDD:271001	199/253 (79%)
		POLO_box_1	388..475	CDD:240561	64/86 (74%)
		POLO_box_2	490..570	CDD:240560	58/79 (73%)
polo	XP_313155.3	STKc_PLK	25..279	CDD:271001	199/253 (79%)
		POLO_box_1	388..475	CDD:240561	63/86 (73%)
		POLO_box_2	490..570	CDD:240560	59/79 (75%)