Protein Alignment polo and plk2

DIOPT Version :9

• Sequence 1: NP_001014592.1
• Gene: polo / 40232
• FlyBaseID: FBgn0003124
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_001096545.1
• Gene: plk2 / 100125189
• XenbaseID: XB-GENE-1006205
• Length: 663
• Species: Xenopus tropicalis
• Alignment Length: 628
• Identity: 216/628 - (34%)
• Similarity: 350/628 - (55%)
• Gaps: 76/628 - (12%)

  Fly     9 STDIPDRLVDINQRKTYKRMRFFGKGGFAKCYEIIDVETDDVFAGKIVSKKLMIKHNQKEKTAQE 73
            :|::...:.|....:.|.|.:..||||||||||:.|:.|:.::|.||:....:.|.:|:||..:|
 Frog    47 ATEVSRIITDPGTGRRYCRGKVLGKGGFAKCYEMTDLTTNKIYAAKIIPHSRVSKPHQREKIDKE 111

  Fly    74 ITIHRSLNHPNIVKFHNYFEDSQNIYIVLELCKKRSMMELHKRRKSITEFECRYYIYQIIQGVKY 138
            |.:||:|||.::|:|::||||.:||||:||.|.:|||..:.|.||.:|:.|.|||:.||:.|:||
 Frog   112 IELHRTLNHRHVVQFYHYFEDKENIYILLEYCSRRSMAHILKTRKVLTDPEVRYYLKQIVSGLKY 176

  Fly   139 LHDNRIIHRDLKLGNLFLNDLLHVKIGDFGLATRIEYEGERKKTLCGTPNYIAPEILTKKGHSFE 203
            ||...|:||||||||.|:|:.:.:|:||||||.|:|...:|::|:||||||::||:|.|:||..|
 Frog   177 LHAQEILHRDLKLGNFFINENMELKVGDFGLAARLEPLEQRRRTICGTPNYLSPEVLNKQGHGCE 241

  Fly   204 VDIWSIGCVMYTLLVGQPPFETKTLKDTYSKIKKCEYRVPSYLRKPAADMVIAMLQPNPESRPAI 268
            .|||::||||||:|:|:|||||..||:||..|::..|.:||.|...|..::.:||..|||.||.:
 Frog   242 SDIWALGCVMYTMLLGRPPFETTNLKETYRCIREARYSLPSSLMTSAKHLIASMLSRNPEDRPNL 306

  Fly   269 GQLLNFEFLKGSKVPMFLPSSCLTMAPRIGSNDTIEDSMHR-------------KPLMEMNGIRP 320
            .::...:|......|..||.||...||....:...::...:             |.|...|.:..
 Frog   307 DEITQHDFFTQGFTPERLPPSCCHTAPDFHLSSPAKNFFKKAAAALFGGKKEKSKYLDNHNKLPK 371

  Fly   321 DDTR-------LESTFLKANLHDAITASAQVCRHSEDY-----------RSDIESLYQQLTNLIN 367
            :|..       |:.:.:...||:.        |..|:.           ::|.:.:...:..::.
 Frog   372 EDEEIYKLRQDLQKSSISHQLHNP--------RTDEEIKTISKLDVLAEKADKQQMGDTIRMIVR 428

  Fly   368 GK-----------------------PRILQG---NLGDENTDPAAQ---PLFWISKWVDYSDKYG 403
            |.                       .|:|:|   |:.|.:..|..|   ...|::||||||:|||
 Frog   429 GTLGSCSSSSECLEDSTMGTVADTVARVLRGCLENMPDADAIPKEQIDTSFHWVTKWVDYSNKYG 493

  Fly   404 FGYQLCDEGIGVMFNDTTKLILLPNQINVHFIDKDGKETYMTTTDYCKSLDKKMKLLSYFKRYMI 468
            |||||.|..:||:||:...:.|||::..||:..:.|..:....|:..:....::.:|.||..||.
 Frog   494 FGYQLSDHTVGVLFNNGAHMNLLPDKKTVHYYAELGPCSVFPATEAPEQFISQVTVLKYFSHYME 558

  Fly   469 EHLVKAGANNVNIESDQISRMPHLHSWFRTTCAVVMHLTNGSVQLNF-SDHMKLILCPRMS--AI 530
            |:|:..|  ::...:|......:|..|.::..|::|...:|:.|:|| .||.|:|:..:..  .:
 Frog   559 ENLMDGG--DLPSVTDVCRPRLYLLQWLKSDKALMMLFNDGTFQVNFYHDHTKIIIANQNDEYLL 621

  Fly   531 TYMDQEKNFRTYRFSTIVENGVSKDLYQKIRYAQEKLRKMLEK 573
            ||:::::...|:|.:|::.:|.|.||..::.||   |..:|::
 Frog   622 TYINEDRMSTTFRLNTLLISGGSSDLKNRMEYA---LNMLLQR 661

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
polo	NP_001014592.1	STKc_PLK	23..277	CDD:271001	127/253 (50%)
		POLO_box_1	388..475	CDD:240561	34/86 (40%)
		POLO_box_2	490..570	CDD:240560	24/82 (29%)
plk2	NP_001096545.1	STKc_PLK2	61..315	CDD:271090	127/253 (50%)
		POLO_box_1	480..566	CDD:240561	35/87 (40%)
		POLO_box_2	579..660	CDD:240560	24/83 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D373288at33208
OrthoFinder	1	1.000	-	-		FOG0000754
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R930
SonicParanoid	1	1.000	-	-		X638
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.950