DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pex23 and lgals8a

DIOPT Version :9

Sequence 1:	NP_730508.1	Gene:	Pex23 / 40229	FlyBaseID:	FBgn0052226	Length:	1350	Species:	Drosophila melanogaster
Sequence 2:	XP_003200715.1	Gene:	lgals8a / 563573	ZFINID:	ZDB-GENE-040724-22	Length:	316	Species:	Danio rerio

Alignment Length:	145	Identity:	39/145 - (26%)
Similarity:	72/145 - (49%)	Gaps:	8/145 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   806 KMDVSTCETPYYNTLYNGMPCGTELEISGCVYDDADQIRFDLQSHSAVKVQPHRVEKHRVIALHL 870
            |..::....||..|:..|:..|..:.|.|.|...:|:.:.||...|::|.:..       :|.|.
Zfish     7 KQTITNPTIPYIGTILGGLQPGEMVLIQGTVPSGSDRFQVDLTCGSSMKPRAD-------VAFHF 64

  Fly   871 NPRFNERT-TVLNSMKESEWLDEIRNDKMAFAPGATFSLKIRALQDHYLIIVNNAVYTDYKYRID 934
            ||||.... .|.|::::..|..|..:..|.|:.||.|.:.|...:|.:.:.||.:...:|:.|::
Zfish    65 NPRFTRSPYIVCNTLQKERWGKEEIHYLMPFSHGAAFEIIILVQKDLFKVAVNGSHLLEYRQRVE 129

  Fly   935 PESVTRLYVSGRIKL 949
            .:.|..|.:||::::
Zfish   130 LKKVDTLNISGKVQI 144

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pex23	NP_730508.1	DysFN	64..125	CDD:214777
		Hyd_WA	210..238	CDD:283993
		Hyd_WA	257..282	CDD:283993
		TECPR	280..320	CDD:214782
		TECPR	338..371	CDD:214782
		PH-like	639..759	CDD:302622
		Gal-bind_lectin	815..954	CDD:278752	38/136 (28%)
		TECPR	966..1000	CDD:214782
		DysFN	1021..1081	CDD:214777
		DysFC	1092..>1113	CDD:128935
		Hyd_WA	1165..1192	CDD:283993
		Hyd_WA	1209..1237	CDD:283993
		Hyd_WA	1308..1333	CDD:283993
lgals8a	XP_003200715.1	Gal-bind_lectin	23..147	CDD:214904	35/129 (27%)
lgals8a	XP_003200715.1	Gal-bind_lectin	193..314	CDD:214904
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	72	1.000	Domainoid score	I9257
eggNOG	1	0.900	-	-		E1_KOG3587
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810