DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pex23 and Lgals4

DIOPT Version :9

Sequence 1:	NP_730508.1	Gene:	Pex23 / 40229	FlyBaseID:	FBgn0052226	Length:	1350	Species:	Drosophila melanogaster
Sequence 2:	XP_008757335.1	Gene:	Lgals4 / 25474	RGDID:	3003	Length:	349	Species:	Rattus norvegicus

Alignment Length:	369	Identity:	73/369 - (19%)
Similarity:	122/369 - (33%)	Gaps:	112/369 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   799 PSEGYVEKMDVSTCETPYYNTLYNGMPCGTELEISGCVYDDADQIRFDL---QSHSAVKVQPHRV 860
            |:.||....:.:   .||...:..|:..|..:.|.|...|:..:...:.   |...|
  Rat     5 PAPGYQPTYNPT---LPYKRPIPGGLSVGMSIYIQGIAKDNMRRFHVNFAVGQDEGA-------- 58

  Fly   861 EKHRVIALHLNPRFNE-RTTVLNSMKESEWLDEIRNDKMAFAPGATFSLKIRALQDHYLIIVNNA 924
                .||.|.||||:. ...|.|:|:..:|..|.:...|.|..|..|.|....:.:||.::||..
  Rat    59 ----DIAFHFNPRFDGWDKVVFNTMQSGQWGKEEKKKSMPFQKGHHFELVFMVMSEHYKVVVNGT 119

  Fly   925 VYTDYKYRIDPESVTRLYVSGRIKLFNVLYRCPSLIVSMERMHWRQMGGHIKRIFNSGVDVVWGI 989
            .:.:|.:|:..:.||.|.|.|.::|.::.:                :||........|...:...
  Rat   120 PFYEYGHRLPLQMVTHLQVDGDLELQSINF----------------LGGQPAASQYPGTMTIPAY 168

  Fly   990 SCDNTGWVYNGGWGGMFLKGL---EGSGKINPMIDTHTYYVYENQRWNPISGFTAKS-------- 1043
            .        :.|:....:..|   .|....||.:.    ||...|     .|.||:.
  Rat   169 P--------SAGYNPPQMNSLPVMAGPPIFNPPVP----YVGTLQ-----GGLTARRTIIIKGYV 216

  Fly  1044 LPTDRHMWSDATGRQKRSKEHTKLLSTHCEWISDWAIDYNIPGGADKEGWQYAIDFPANYHAHKK 1108
            |||.:::                            .|::.:....|           ..:|.:.:
  Rat   217 LPTAKNL----------------------------IINFKVGSTGD-----------IAFHMNPR 242

  Fly  1109 LTDCVRRRRWMKRCRLSSSG------PWQELSQSKILDAALQVL 1146
            :.|||.|..:|.    .|.|      |:......:..|.:|.||
  Rat   243 IGDCVVRNSYMN----GSWGSEERKIPYNPFGAGQFFDVSLGVL 282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pex23	NP_730508.1	DysFN	64..125	CDD:214777
		Hyd_WA	210..238	CDD:283993
		Hyd_WA	257..282	CDD:283993
		TECPR	280..320	CDD:214782
		TECPR	338..371	CDD:214782
		PH-like	639..759	CDD:302622
		Gal-bind_lectin	815..954	CDD:278752	38/142 (27%)
		TECPR	966..1000	CDD:214782	3/33 (9%)
		DysFN	1021..1081	CDD:214777	9/67 (13%)
		DysFC	1092..>1113	CDD:128935	2/20 (10%)
		Hyd_WA	1165..1192	CDD:283993
		Hyd_WA	1209..1237	CDD:283993
		Hyd_WA	1308..1333	CDD:283993
Lgals4	XP_008757335.1	Gal-bind_lectin	24..148	CDD:214904	36/135 (27%)
Lgals4	XP_008757335.1	Gal-bind_lectin	201..348	CDD:214904	22/130 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3587
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810