DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pex23 and lec-4

DIOPT Version :9

Sequence 1:	NP_730508.1	Gene:	Pex23 / 40229	FlyBaseID:	FBgn0052226	Length:	1350	Species:	Drosophila melanogaster
Sequence 2:	NP_497763.1	Gene:	lec-4 / 175488	WormBaseID:	WBGene00002267	Length:	283	Species:	Caenorhabditis elegans

Alignment Length:	244	Identity:	51/244 - (20%)
Similarity:	83/244 - (34%)	Gaps:	63/244 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   791 MKAHQTSEPSEGYVEKMDVSTCETPYYNTLYNGMPCGTELEISGCVYDDADQIRFDLQSHSAVKV 855
            |.:|:...|            ...||.:.|...:..|..|.:.|.:.:.|.....:|.....
Worm     1 MSSHENDTP------------LPVPYTSRLGQPLDAGQTLNVHGKINEGAQVAEINLLQGGG--- 50

  Fly   856 QPHRVEKHRVIALHLNPRFNERTTVLNSMKESEWLDEIRNDKMAFAPGATFSLKIRALQDHYLII 920
               .:..:..:.|||...|.|:..:|||.:...|..|.| :.:.|..|..|.|:||.|.:...|.
Worm    51 ---EIGPNTQVILHLKLNFKEKKVILNSYENGVWGKEER-ESLPFQAGQEFDLRIRVLDEGLEIS 111

  Fly   921 VNNAVYTDYKYRIDPESVTRLYVSGRIKLFNVLYRCPSLIVSMERMHWRQMGGHIKRIFNSGVDV 985
            .:|....::|:|:..:|:..|.|.|.:              |:..:||   ||..
Worm   112 ADNKKIHEFKHRLPFQSIEYLSVRGDL--------------SLNGIHW---GGRF---------- 149

  Fly   986 VWGISCDNTGWVYNGGWGGMFLKGLEGSGKINPMIDTHTYYVYENQRWN 1034
                        |...|...|..|....|:     ..|.|.:.:..||:
Worm   150 ------------YKLPWETAFPAGFLEKGQ-----RVHLYGIPKGDRWS 181

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pex23	NP_730508.1	DysFN	64..125	CDD:214777
		Hyd_WA	210..238	CDD:283993
		Hyd_WA	257..282	CDD:283993
		TECPR	280..320	CDD:214782
		TECPR	338..371	CDD:214782
		PH-like	639..759	CDD:302622
		Gal-bind_lectin	815..954	CDD:278752	34/138 (25%)
		TECPR	966..1000	CDD:214782	5/33 (15%)
		DysFN	1021..1081	CDD:214777	4/14 (29%)
		DysFC	1092..>1113	CDD:128935
		Hyd_WA	1165..1192	CDD:283993
		Hyd_WA	1209..1237	CDD:283993
		Hyd_WA	1308..1333	CDD:283993
lec-4	NP_497763.1	GLECT	14..145	CDD:214596	34/151 (23%)
lec-4	NP_497763.1	GLECT	154..282	CDD:214596	8/33 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3587
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810