Protein Alignment Pex23 and T01H3.2

DIOPT Version :10

• Sequence 1: NP_730508.1
• Gene: Pex23 / 40229
• FlyBaseID: FBgn0288469
• Length: 1350
• Species: Drosophila melanogaster
• Sequence 2: NP_495658.1
• Gene: T01H3.2 / 174271
• WormBaseID: WBGene00011348
• Length: 980
• Species: Caenorhabditis elegans
• Alignment Length: 1425
• Identity: 262/1425 - (18%)
• Similarity: 454/1425 - (31%)
• Gaps: 557/1425 - (39%)

  Fly     1 MPSFYLFAASSEGRVYTLSTNSG-------AWRELPYL-GLEFKKICAVPNFLWAIGGDRQVYVH 57
            ||..|::..|:.|....:.:.|.       .|:|:|.. |.....|.|.|...:||....:|.:.
 Worm     1 MPFEYIWTVSANGVACRIPSPSDPRCISEIEWKEIPCSDGSAICTIVASPTSAFAIDRSGRVLIL 65

  Fly    58 VHGLDVPIRIREESYENERWLPIEGFSKTLLPTDRYRYSSADG--SVERGVDKIRLPSMAWQWDG 120
            |....:.||.|.|.|.|:||:   |..:.....||.|:|...|  |::...::|   ...|.|:.
 Worm    66 VLPTHLAIRERAEIYNNQRWI---GIWRGTFFIDRPRFSDESGRVSIDPSANEI---DPGWSWED 124

  Fly   121 DWHLDLELDGQPLTEDGWMYALDFPATYSAKKSWNS------YVRRRKWVRYRRYAALNSWCAVA 179
            :||  ..||.:...::||.|:|.|.|     ..|:.      .||||...|..||.:.:.|..::
 Worm   125 NWH--PHLDPRKYDKEGWQYSLSFLA-----PKWDKQCRMYHLVRRRVLKRNVRYTSHDQWIEMS 182

  Fly   180 PLHKDPTQEPFIDVAIGGTCVPNAPAGTLCVWAITAHGRAMFRTGVSKTAPEGLRWTAVPTPT-- 242
                :.....|.::||||..|..  .|.:.::|:.:.|....|.|:..:.|.|..|..:...|
 Worm   183 ----NEETRMFTELAIGGMDVMG--EGGMILFALGSDGNIYRRDGIHPSCPSGRSWQLISKVTFK 241

  Fly   243 ---GSELAQISVGPT-GLVWAVLHNGRVIVRTGVTRDNLVGDSWLDVKTPVAASSLRIVHVSVGT 303
               ..::..||..|: ..:.|:..:|::..|.|:||.|..|.||..:.||   .:..::..|:||
 Worm   242 DCESDDVTLISASPSLATLMAITWDGKMFHRVGITRQNQNGFSWKSIPTP---KNKAVISASIGT 303

  Fly   304 DAVWCVTNDHHAWFRRGVKGEAAGISEDSAIGKGWVEMV----------GNISMVSVAANDQVFA 358
            ..:||:|.|...||.|        :..|..:.:..:|.:          |.||.:||..|||||.
 Worm   304 RTMWCITADGCVWFVR--------LDIDEKLKEHKMENITSESYQMTTQGGISKISVTRNDQVFC 360

  Fly   359 IGAADRCLYHRSGVTSADPTGKKWRLIQCPMQISRTSSS----LSIVSRKSGGS---SSTPGSKH 416
            :...:: :..|:|:...:|:||::..|     :.|...:    :||.:    ||   ...| ...
 Worm   361 VSTREK-IEVRTGIEPREPSGKRFERI-----VDRGEPNDQKWISIHT----GSVLFDKIP-DYF 414

  Fly   417 QSFSNLYSKEKEKGVVETCAVIETVLNSSTGSCSSNGGPPGLLKNERWKLSADSPPTIGSLNLND 481
            .|.|:|.||.:             ||.               .|...|:|
 Worm   415 MSSSSLKSKME-------------VLQ---------------FKKADWRL--------------- 436

  Fly   482 RHKQRTAALRETSHASSAPAADVVEVVTGKFETQLRNPRAWSPVRSVGSVVGTEAHPESDSTVFE 546
               |....|:|||                        .|:||.:.||.. ||.:: ||.
 Worm   437 ---QILERLQETS------------------------DRSWSLMNSVNG-VGIDS-PEE------ 466

  Fly   547 SDSTHHGSDVFLGEDDDHTGSQFWTECGILWSCVASGAVTVDASNMPNWFNEQTSDSKV--DVNA 609
                                                    ::..|.|.....|....::  .||.
 Worm   467 ----------------------------------------LEGPNTPRQIRCQLMQGELFRSVNI 491

  Fly   610 NWRKDIVNKLQRRQEKLAKLQTVA--KFEKAVELSSWVKSADARYQRPGGEFEDCIIELEWVSSG 672
            .    |:|.         .||...  ...|:::.|| :||....:||...::      |.:|..|
 Worm   492 T----ILNN---------NLQIYGDNSLSKSIDTSS-IKSVLPCFQRLPQKY------LLYVFIG 536

  Fly   673 SGTDTN----SSENSRSGDSGTFTVLSPDGAATKIQFPLSDITCVQCCSEAGAPRIAIHAPHLPV 733
            :.:|:.    :.|.||:    ||
 Worm   537 ANSDSECFAFTDEKSRT----TF------------------------------------------ 555

  Fly   734 NCSPVKLQFSSDSEMEDWLSHLSSVCSQINTMVGKPAGNAIWITSELGDVFVFDPANMKAHQTSE 798
                   |...::.:.|:      :||......    |:.:|..|..|.|        :.|..:|
 Worm   556 -------QSILETIIRDY------ICSSTRNSF----GDCMWSISSEGVV--------RWHCLAE 595

  Fly   799 PSE--GYVEKMDVSTCETPYYNTLYNGMPCGTE-----LEISGCVYDDADQIRFDLQSHSAVKVQ 856
            .|:  .:.::::.........:.|:..:.||.:     :..||.:|.
 Worm   596 MSKESKFEKRVNPGESRGLVVDGLFESVDCGVKGSVWAINQSGNLYS------------------ 642

  Fly   857 PHRVEKHRVIALHLNPRFNERTTVLNSMKESEWLDEIRNDKMAFAPGATFSLKIRALQDHYLIIV 921
                     ::.:.||..:..||     .:.:..|:|             :||:...|.|
 Worm   643 ---------LSSNYNPLSSHSTT-----HDYKMTDQI-------------TLKMFEYQKH----- 675

  Fly   922 NNAVYTDYKYRIDPESVTRLYVSGRIKLFNVLYRCPSLIVSMERMHWRQMGGHIKRIFNSGVDVV 986
                           :|.|.::|
 Worm   676 ---------------AVFRGFIS------------------------------------------ 683

  Fly   987 WGISCDNTGWVYNGGWGGMFLKGLEGSGKINPMIDTHTYYVYENQRWNPISGFTAKSLPTDRHMW 1051
                       :.|...|:                  :.::.:|:...|    :..|||
 Worm   684 -----------FQGSQKGI------------------SAWMCDNKPCPP----SPSSLP------ 709

  Fly  1052 SDATGRQKRSKEHTKLLSTHCEWI-SDWAIDYNIPGGADKEGWQYAIDFPANYHAHKKLTDCVRR 1115
                             ||:..|| |.|.:        :::.|:|:.:....|..::|.....||
 Worm   710 -----------------STNWSWIDSAWQL--------EEDTWKYSNNIDGVYSYNEKAQGKARR 749

  Fly  1116 RRWMKRCRLS-SSGPWQELSQSKILDAALQVLDEDVDHSCSGERNTAVAAWAIASNGDVLIRHGV 1179
            |.|.::.:.. :..||..:....|....:..::     ||.|    .:....:..:|.:|||:||
 Worm   750 RVWRRQAKFELNKSPWCHVESPPIQCVRVSKIE-----SCEG----TIVVVVLTKDGHILIRNGV 805

  Fly  1180 CSLNPRGDAWEHITSDQPLVGISVGPTG-QVWTVARNGMVFFRYGISRQNPCGDA------WQQV 1237
            ...:..|..|..|.:|.|:..:.:...| ::|....:|.:..|   |..|....:      |:.:
 Worm   806 DREHFTGTNWTEILTDSPISSMHLQWEGMKLWCATYDGTILSR---SLTNSKSSSFLSSSDWRHL 867

  Fly  1238 EAPAGVTFKAIS---------VGRAGI---------WALDNQQRLAVRKEISRTFPEGSHWQFLP 1284
            :....|....||         .|.:.|         :.:|.:     .:.||..:|..:..|.:
 Worm   868 DLDTSVITDNISPKAVNDIELTGYSDILYVRIKFILFRIDTK-----NETISDAYPMDNLQQAV- 926

  Fly  1285 NAANVPPHTDQHCGFRSVSVGSEVWAISLNGIICRRCGITEENPAGVGWNLGIAGQWQNV 1344
                                      :|..|.||.|           |.|:.:...|:.|
 Worm   927 --------------------------VSARGSICLR-----------GTNITVVRDWRVV 949

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pex23	NP_730508.1	DysFN	64..125	CDD:214777	20/62 (32%)
		Tectonin	210..398	CDD:465992	52/207 (25%)
		PH-like	639..759	CDD:473070	17/123 (14%)
		Gal-bind_lectin	821..953	CDD:459768	18/136 (13%)
		TECPR	966..1000	CDD:214782	0/33 (0%)
		DysFN	1021..1081	CDD:214777	11/60 (18%)
		DysFC	1092..>1113	CDD:128935	4/20 (20%)
		Tectonin	<1165..1333	CDD:465992	33/192 (17%)
T01H3.2	NP_495658.1	DysFN	72..129	CDD:214777	20/64 (31%)
		Hyd_WA	207..235	CDD:461921	7/27 (26%)
		Hyd_WA	259..288	CDD:461921	10/28 (36%)
		DysFN	662..723	CDD:214777	22/199 (11%)
		DysFC	726..759	CDD:128935	8/32 (25%)