Protein Alignment FRG1 and FRG1

DIOPT Version :9

• Sequence 1: NP_649202.1
• Gene: FRG1 / 40228
• FlyBaseID: FBgn0036964
• Length: 262
• Species: Drosophila melanogaster
• Sequence 2: NP_004468.1
• Gene: FRG1 / 2483
• HGNCID: 3954
• Length: 258
• Species: Homo sapiens
• Alignment Length: 270
• Identity: 130/270 - (48%)
• Similarity: 173/270 - (64%)
• Gaps: 20/270 - (7%)

  Fly     1 MSDYDHARIKKLVLKGEKLK------KSKKRKKEKDEAGSSKKAKVVVDEDAVKHGGWWAAKTAA 59
            |::|.:.:..||||||.|.|      |.||||:|:||.         ...|.|  |.||......
Human     1 MAEYSYVKSTKLVLKGTKTKSKKKKSKDKKRKREEDEE---------TQLDIV--GIWWTVTNFG 54

  Fly    60 DITGTVSIEFGDRSYLKAMDNGLFTLGAPHNAGD-GPDPEEIFTAFPINDRKVAFKSGYGKYLKI 123
            :|:||::||....:|:.|:|||||||||||...| ||.|.|.|||..::|.::|.||||||||.|
Human    55 EISGTIAIEMDKGTYIHALDNGLFTLGAPHKEVDEGPSPPEQFTAVKLSDSRIALKSGYGKYLGI 119

  Fly   124 EKDGMVTGRSEAVGGMEQWEPVFEEQRMALLSETGHFMSIDPQDDACVALRKKVGQHEICKVRSN 188
            ..||:|.|||:|:|..|||||||:..:||||:....|:..:...| ..|..|..|:.|:.|:||.
Human   120 NSDGLVVGRSDAIGPREQWEPVFQNGKMALLASNSCFIRCNEAGD-IEAKSKTAGEEEMIKIRSC 183

  Fly   189 ASRDV-VIDTEPKEEKGDLGEVEKNYVKKFQKFQDKKMRINQNDVKELEQAKAQGSLHETLLDRR 252
            |.|:. ..|..|:|:||::.:.|.|||||||.|||.|::|::.|.|.|::|:..|.|||||||||
Human   184 AERETKKKDDIPEEDKGNVKQCEINYVKKFQSFQDHKLKISKEDSKILKKARKDGFLHETLLDRR 248

  Fly   253 SKMKADRYCK 262
            :|:|||||||
Human   249 AKLKADRYCK 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FRG1	NP_649202.1	FRG1	72..260	CDD:283809	98/189 (52%)
FRG1	NP_004468.1	Nuclear localization signal. /evidence=ECO:0000255	22..32		6/9 (67%)
		FRG1	67..256	CDD:368803	97/190 (51%)
		Bipartite nuclear localization signal. /evidence=ECO:0000255	235..251		9/15 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151673
Domainoid	1	1.000	194	1.000	Domainoid score	I3181
eggNOG	1	0.900	-	-		E1_KOG3962
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3295
Inparanoid	1	1.050	239	1.000	Inparanoid score	I3362
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52298
OrthoDB	1	1.010	-	-		D1400930at2759
OrthoFinder	1	1.000	-	-		FOG0006139
OrthoInspector	1	1.000	-	-		oto88456
orthoMCL	1	0.900	-	-		OOG6_105059
Panther	1	1.100	-	-	LDO	PTHR12928
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R457
SonicParanoid	1	1.000	-	-		X5071
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800