Protein Alignment CG17122 and CFAP157

DIOPT Version :10

• Sequence 1: NP_730506.1
• Gene: CG17122 / 40226
• FlyBaseID: FBgn0036962
• Length: 598
• Species: Drosophila melanogaster
• Sequence 2: NP_001012520.2
• Gene: CFAP157 / 286207
• HGNCID: 27843
• Length: 520
• Species: Homo sapiens
• Alignment Length: 529
• Identity: 124/529 - (23%)
• Similarity: 248/529 - (46%)
• Gaps: 111/529 - (20%)

  Fly     3 PKVKKEKKDVNKVTQVDRTFYELTITDLNQKLARLRSHVTTVDESNITLTEKLKEVEADGVDVAA 67
            |.:.||.|:          ||.:.|.||..:|||.:.....:........::.:::..:..::.|
Human    31 PPLAKEMKE----------FYHIQIRDLEDRLARYQRKWDELAVQEKMFRQEFEQLANNKKEIVA 85

  Fly    68 HLERTLAERNNSITELEERLVEITKVRDVENRVAQEKIGDLESKYKAMHDQLTSEIKLLNGKLNS 132
            .|:|||.::.:.||:|.|:|..:...:::|....:.::..:..:::...||||:|..:|.|||.:
Human    86 FLKRTLNQQVDEITDLNEQLQNLQLAKEMEKDAFEAQLAQVRHEFQETKDQLTTENIILGGKLAA 150

  Fly   133 LDEFRIQRDVLLAKFDEQEADLNEREKDHKEALYNMEQRAVVEKDALKKEVEQKLLQVSEDFTRS 197
            |:|||:|::.:..||...|..:.::|.:.::..||:|:::|::||.|:||:.|::..|:.:|.:.
Human   151 LEEFRLQKEEVTDKFTLLEEQVRKQENEFRDYAYNLEKKSVLDKDRLRKEIIQRVNLVANEFHKV 215

  Fly   198 SEIRNAGYTRRLIRENIALQKEIDLLVMSQIKLQQAYTNQKSKHKEMEEQYSALDQIKNELVRNS 262
            :..|....|:|.|:||            :.|.||.|..:|:.. |.::|         ||.::..
Human   216 TTNRMWETTKRAIKEN------------NGITLQMARVSQQGM-KLLQE---------NEQLKGR 258

  Fly   263 VNKI-KIIEGLTRNYEKLKAKYVEVLRYKKAYES--LLQAEKCENVKQKDA--AGKLRTLAKRME 322
            .|.: |.:| |..|.:|:.|      |:|:.::.  |:..:||:. :|:|.  |.:||.|..::|
Human   259 QNNLCKQLE-LLENTQKVMA------RHKRGHQKIILMLTKKCQE-QQQDTKEAEELRLLLSQLE 315

  Fly   323 ----ILDLDNR-------NLEVVHAQHEIEITRLRGVI---QEIKCTVRDAIVAEQAAKKFPERL 373
                .|.:||:       .|.:...|.::::.||:..:   |:::.::..|:|   .|..|.:.:
Human   316 QRSLQLQVDNQALKSQRDQLSLQLEQQQVDLQRLQQELANEQKVRASLEAALV---QATSFLQNI 377

  Fly   374 VEANVDDPAMINEVREEAISLCKLKRSDLLSQLMSIVSS------------HSE----------- 415
            ::.:.|:.....:|..:.      ...::|.||:.::||            |.|
Human   378 LQMHRDEEDSDVDVTFQP------WHKEMLQQLLVMLSSTVATRPQKAACPHQESQSHGPPKESR 436

  Fly   416 ---ELPKTPSIASIVSATSSLYAPGKMGFMPTRPKATP-------------FDAFRSEVIEQEPD 464
               :||:|.|:...:|..:. |.||.:|.:|.:....|             ...||:   ...|:
Human   437 PSIQLPRTGSLLPQLSDITP-YQPGDLGLVPRQVHIPPNPQDLRLLSYITRVGTFRA---HSSPE 497

  Fly   465 RTVPEDLQK 473
            ...|..|::
Human   498 MRAPGSLKR 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17122	NP_730506.1	Smc	<24..>399	CDD:440809	95/393 (24%)
CFAP157	NP_001012520.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..22
		SMC_prok_B	<45..>331	CDD:274008	84/315 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	416..453		6/36 (17%)