DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rdgC and CanA-14F

DIOPT Version :9

Sequence 1:	NP_536738.3	Gene:	rdgC / 40224	FlyBaseID:	FBgn0265959	Length:	746	Species:	Drosophila melanogaster
Sequence 2:	NP_001245717.1	Gene:	CanA-14F / 8674098	FlyBaseID:	FBgn0267912	Length:	584	Species:	Drosophila melanogaster

Alignment Length:	388	Identity:	106/388 - (27%)
Similarity:	174/388 - (44%)	Gaps:	77/388 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   147 AAGRKNQYQGSAHV----------SVLDDKDDLVEEF----------GDIVNAKIELP---IRKN 188
            :||.:.|.||....          |.:..|:.:::..          .|:.:|:...|   :.|.
  Fly    58 SAGTQQQGQGGTGTSSGPSSPTKRSTISTKERVIDSVAFPPSRKLTCADVFDARTGKPQHDVLKQ 122

  Fly   189 HIDLLIDVFRKKRGNRLHPKYVALILREAAKSLKQLPNISPVSTAVSQQVTVCGDLHGKLDDLLV 253
            |..|         ..|:.......|::|.|..|:    .......:...||||||:||:..||:.
  Fly   123 HFIL---------EGRIEESAALRIIQEGATLLR----TEKTMIDIEAPVTVCGDIHGQFYDLMK 174

  Fly   254 VLHKNGLPSSSNPYVFNGDFVDRGKRGLEVLLLLLSLYLAFPNAVFLNRGNHEDSVMNARYGFIR 318
            :....|.|:::. |:|.||:||||...:|.:|.|.||.:.:|..:||.|||||...:...:.|.:
  Fly   175 LFEIGGSPATTK-YLFLGDYVDRGYFSIECVLYLWSLKITYPQTLFLLRGNHECRHLTEYFTFKQ 238

  Fly   319 EVESKYPRNHKRILAFIDEVYRWLPLGSVLNSRVLIVHGGFS-DSTSLDLIKSIDRGKYVSILRP 382
            |.:.||   .:|:.....:.:..|||.:::|.:.|.||||.| :...|:.|:.:||.|     .|
  Fly   239 ECKIKY---SERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEIHELEDIRRLDRFK-----EP 295

  Fly   383 PLTDGEPLDKTEWQQIFDIMWSDPQATMG-------CVPNTLRGAGVWFGPDVTDNFLQRHRLSY 440
            |          .:..:.|::||||....|       ...|::||...::......:|||.:.|..
  Fly   296 P----------AFGPMCDLLWSDPLEDFGNEKNSDFYTHNSVRGCSYFYSYAACCDFLQNNNLLS 350

  Fly   441 VIRSHECKPNGHEFMHDNK------IITIFSASNYYAIGSNKGAYIRLNNQLM--------PH 489
            :||:||.:..|:.....::      :||||||.||..:.:||.|.::..|.:|        ||
  Fly   351 IIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPH 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rdgC	NP_536738.3	IQ	89..111	CDD:197470
		MPP_RdgC	184..494	CDD:277364	97/331 (29%)
		EFh	616..681	CDD:238008
CanA-14F	NP_001245717.1	MPP_PP2B	115..419	CDD:277361	97/331 (29%)
CanA-14F	NP_001245717.1	PP2Ac	132..403	CDD:197547	89/293 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438802
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930