DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rdgC and PPQ1

DIOPT Version :9

Sequence 1:	NP_536738.3	Gene:	rdgC / 40224	FlyBaseID:	FBgn0265959	Length:	746	Species:	Drosophila melanogaster
Sequence 2:	NP_015146.1	Gene:	PPQ1 / 855923	SGDID:	S000006100	Length:	549	Species:	Saccharomyces cerevisiae

Alignment Length:	312	Identity:	93/312 - (29%)
Similarity:	148/312 - (47%)	Gaps:	24/312 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   199 KKRGNRLHPKYVALILREAAKSLKQLPNISPVSTAVSQQVTVCGDLHGKLDDLLVVLHKNGLPSS 263
            ||:....|...:.||...|.:.....|.:    ..:...:.|.||:||:.:|||.:|..:|:||.
Yeast   261 KKKNFPFHSWEIQLICYHAREIFLNQPTL----LRLQAPIKVVGDVHGQFNDLLRILKLSGVPSD 321

  Fly   264 SNPYVFNGDFVDRGKRGLEVLLLLLSLYLAFPNAVFLNRGNHEDSVMNARYGFIREVESKYPRNH 328
            :| |:|.||:|||||..||.:||||...:.:.:..|:.|||||.:.:...|||..|.:.:.  :.
Yeast   322 TN-YLFLGDYVDRGKNSLETILLLLCYKIKYKDNFFMLRGNHESANVTKMYGFYDECKRRL--SS 383

  Fly   329 KRILAFIDEVYRWLPLGSVLNSRVLIVHGGFS-DSTSLDLIKSIDRGKYVSILRPPLTDGEPLDK 392
            |....|:| |:..|||.:::..::..||||.| |...:..|:.:.|               |.|.
Yeast   384 KVWKMFVD-VFNTLPLAAIIQDKIFCVHGGISPDLHDMKQIEKVAR---------------PTDI 432

  Fly   393 TEWQQIFDIMWSDPQATMGCVPNTLRGAGVWFGPDVTDNFLQRHRLSYVIRSHECKPNGHEFMHD 457
            .|...:.|::||||...:.......||....|......:|..:.:...::|.|....:|:||...
Yeast   433 PESGLVTDLLWSDPDPQVTDWSENDRGVSYTFSKRNVLDFCAKFKFDLILRGHMVVEDGYEFFAR 497

  Fly   458 NKIITIFSASNYYAIGSNKGAYIRLNNQLMPHFVQYISAASQTKRLSFKQRM 509
            .|.:|||||.||.....|.||.:.:...:|..|......|.:.|:..:|.::
Yeast   498 KKFVTIFSAPNYCGEFHNWGAVMSVTTGMMCSFELLKPRALKNKKKLYKTKV 549

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rdgC	NP_536738.3	IQ	89..111	CDD:197470
		MPP_RdgC	184..494	CDD:277364	90/295 (31%)
		EFh	616..681	CDD:238008
PPQ1	NP_015146.1	MPP_PP1_PPKL	239..535	CDD:277359	90/296 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000