Protein Alignment rdgC and CMP2

DIOPT Version :10

• Sequence 1: NP_536738.3
• Gene: rdgC / 40224
• FlyBaseID: FBgn0265959
• Length: 746
• Species: Drosophila melanogaster
• Sequence 2: NP_013655.1
• Gene: CMP2 / 854946
• SGDID: S000004521
• Length: 604
• Species: Saccharomyces cerevisiae
• Alignment Length: 608
• Identity: 146/608 - (24%)
• Similarity: 244/608 - (40%)
• Gaps: 139/608 - (22%)

  Fly   157 SAHVSVLDDKDDLVE---EFGDIV--NAKI--ELPIRKNHI---------------DLLIDVFRK 199
            :|:.:..:...||.:   :.|.:|  |.:|  ::|...:|:               :.|.|.|
Yeast    42 AANSTATETSRDLTQYTLDDGRVVSTNRRIMNKVPAITSHVPTDEELFQPNGIPRHEFLRDHF-- 104

  Fly   200 KRGNRLHPKYVALILREAAKSLKQLPNISPVSTAVSQQVTVCGDLHGKLDDLLVVLHKNGLPSSS 264
            ||..:|.....|.|:..|.:...:.||:    .:|...:|||||:||:..|||.:....|.|:::
Yeast   105 KREGKLSAAQAARIVTLATELFSKEPNL----ISVPAPITVCGDIHGQYFDLLKLFEVGGDPATT 165

  Fly   265 NPYVFNGDFVDRGKRGLEVLLLLLSLYLAFPNAVFLNRGNHEDSVMNARYGFIREVESKYPRNHK 329
            : |:|.||:||||....|.|:.|.||.|.|.:..:|.|||||...:.:.:.|..|:..||   :.
Yeast   166 S-YLFLGDYVDRGSFSFECLIYLYSLKLNFNDHFWLLRGNHECKHLTSYFTFKNEMLHKY---NL 226

  Fly   330 RILAFIDEVYRWLPLGSVLNSRVLIVHGGFS-DSTSLDLIKSIDRGKYVS--------ILRPPLT 385
            .|.....|.:..|||.:::|.:.|.||||.| :..||..|.:::|.:.:.        :...|:.
Yeast   227 DIYEKCCESFNNLPLAALMNGQYLCVHGGISPELNSLQDINNLNRFREIPSHGLMCDLLWADPIE 291

  Fly   386 D-GEPLDKTEWQQIFDIMWSD----------PQATMGCVPNTLRGAGVWFGPDVTDNFLQRHRLS 439
            : .|.|||...::  ||:.|.          |...| .|||::||....|......:|||...|.
Yeast   292 EYDEVLDKDLTEE--DIVNSKTMVPHHGKMAPSRDM-FVPNSVRGCSYAFTYRAACHFLQETGLL 353

  Fly   440 YVIRSHECKPNGHEFMHDNK------IITIFSASNYYAIGSNKGAYIRLNNQLM----------- 487
            .:||:||.:..|:....:.|      ::|:|||.||....:||.|.::..|.:|
Yeast   354 SIIRAHEAQDAGYRMYKNTKTLGFPSLLTLFSAPNYLDTYNNKAAILKYENNVMNIRQFNMTPHP 418

  Fly   488 ---PHFVQYISAASQTKRLSFKQRMGIVESSALKELAVRMRD--HRDELEDE------------- 534
               |.|:...     |..|.|       ....:.|:.|.:.:  ..||||::
Yeast   419 YWLPDFMDVF-----TWSLPF-------VGEKVTEMLVAILNICTEDELENDTPVIEELVGTDKK 471

  Fly   535 -------------FRKYDPKDSGYISISHWCKVMEN----VTKLGLPWRLLRDKLAPGTDSQKVN 582
                         .....||.:..:...|..|.:.|    |.|:...:.:||:      ::.||.
Yeast   472 LPQAGKSEATPQPATSASPKHASILDDEHRRKALRNKILAVAKVSRMYSVLRE------ETNKVQ 530

  Fly   583 YNRTLDLLDTDVILEAEADGMSVMDALYANKASLVAIFNIIDADNSGEITLDEFETAIDLLVAHM 647
            :            |:....|:....||......|....:..:.....::..::...::|.|....
Yeast   531 F------------LKDHNSGVLPRGALSNGVKGLDEALSTFERARKHDLINEKLPPSLDELKNEN 583

  Fly   648 PGAYSKAEMLEKCRMMDLNGDGK 670
            ...|.|  :.:|....|...|.|
Yeast   584 KKYYEK--VWQKVHEHDAKNDSK 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rdgC	NP_536738.3	IQ	89..111	CDD:197470
		MPP_RdgC	184..494	CDD:277364	106/364 (29%)
		FRQ1	527..681	CDD:444056	28/174 (16%)
		EFh	616..681	CDD:238008	9/55 (16%)
CMP2	NP_013655.1	MPP_PP2B	95..423	CDD:277361	102/340 (30%)