DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rdgC and PPH3

DIOPT Version :9

Sequence 1:	NP_536738.3	Gene:	rdgC / 40224	FlyBaseID:	FBgn0265959	Length:	746	Species:	Drosophila melanogaster
Sequence 2:	NP_010360.1	Gene:	PPH3 / 851647	SGDID:	S000002482	Length:	308	Species:	Saccharomyces cerevisiae

Alignment Length:	293	Identity:	102/293 - (34%)
Similarity:	158/293 - (53%)	Gaps:	27/293 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   213 ILREAAKSLKQLPNISPVSTAVSQQVTVCGDLHGKLDDLLVVLHKNGLPSSSNPYVFNGDFVDRG 277
            :.|....|.:.|.|...| |.|...||:|||:||:|.|||.:..|:|....:. |:|.|||||||
Yeast    22 VFRLCLNSQELLMNEGNV-TQVDTPVTICGDIHGQLHDLLTLFEKSGGVEKTR-YIFLGDFVDRG 84

  Fly   278 KRGLEVLLLLLSLYLAFPNAVFLNRGNHEDSVMNARYGFIREVESKYPRNHKRILAFIDEVYRWL 342
            ...||..||||...|.:|:.:.|.|||||...:...|||..||..||  .:..:..:..||:.:|
Yeast    85 FYSLESFLLLLCYKLRYPDRITLIRGNHETRQITKVYGFYDEVVRKY--GNSNVWRYCCEVFDYL 147

  Fly   343 PLGSVLNSRVLIVHGGFS-DSTSLDLIKSIDRGKYVSILRPPLTDGEPLDKTEWQQIFDIMWSDP 406
            .||:::|:.:..||||.| |.|::|.|::|||.:.|.      .:|         .:.|::||||
Yeast   148 SLGAIINNSIFCVHGGLSPDMTTVDEIRTIDRKQEVP------HEG---------AMCDLLWSDP 197

  Fly   407 Q--ATMGCVPNTLRGAGVWFGPDVTDNFLQRHRLSYVIRSHECKPNGHEFMHDNKIITIFSASNY 469
            :  .|....|   ||||..||....|.||:::.:..:.|:|:....|::.|.|..::|::||.||
Yeast   198 EDVDTWSLSP---RGAGFLFGKREVDQFLEKNNVELIARAHQLVMEGYKEMFDGGLVTVWSAPNY 259

  Fly   470 -YAIGSNKGAYIRLNNQLMPHFVQYISAASQTK 501
             |..| |..|.:::::.|...:..:.:..:|.:
Yeast   260 CYRCG-NVAAVLKIDDDLNREYTIFEAVQAQNE 291

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rdgC	NP_536738.3	IQ	89..111	CDD:197470
		MPP_RdgC	184..494	CDD:277364	101/284 (36%)
		EFh	616..681	CDD:238008
PPH3	NP_010360.1	MPP_PP2A_PP4_PP6	3..286	CDD:277360	101/286 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910