Protein Alignment rdgC and CNA1

DIOPT Version :10

• Sequence 1: NP_536738.3
• Gene: rdgC / 40224
• FlyBaseID: FBgn0265959
• Length: 746
• Species: Drosophila melanogaster
• Sequence 2: NP_013537.1
• Gene: CNA1 / 851153
• SGDID: S000004425
• Length: 553
• Species: Saccharomyces cerevisiae
• Alignment Length: 609
• Identity: 149/609 - (24%)
• Similarity: 232/609 - (38%)
• Gaps: 182/609 - (29%)

  Fly   163 LDDKDDLVE---EFGDIVNAK----IELPIRKNHIDLLIDVFRKKRG--------------NRLH 206
            :|.|.||.:   |.|.:::.|    ..:|.....|....:||..|.|              .||.
Yeast    22 VDRKKDLTKYELENGKVISTKDRPIASVPAITGKIPSDEEVFDSKTGLPNHSFLREHFFHEGRLS 86

  Fly   207 PKYVALILREAAKSLKQLPNISPVSTAVSQQVTVCGDLHGKLDDLLVVLHKNGLPSSSNPYVFNG 271
            .:....||..:..:|.:.||:    ..:...:|:|||:||:..|||.:....|.|:..: |:|.|
Yeast    87 KEQAIKILNMSTVALSKEPNL----LKLKAPITICGDIHGQYYDLLKLFEVGGDPAEID-YLFLG 146

  Fly   272 DFVDRGKRGLEVLLLLLSLYLAFPNAVFLNRGNHEDSVMNARYGFIREVESKYPRNHKRILAFID 336
            |:||||....|.|:.|.||.|......::.|||||...:.:.:.|..|:..||..
Yeast   147 DYVDRGAFSFECLIYLYSLKLNNLGRFWMLRGNHECKHLTSYFTFKNEMLHKYDM---------- 201

  Fly   337 EVY-------RWLPLGSVLNSRVLIVHGGFSDSTSLDLIKSIDRGKYVSILRPPLTDGEPLDKTE 394
            |||       ..|||.:::|.:...||||.|..     :||::....::..|...:.|
Yeast   202 EVYDACCRSFNVLPLAALMNGQYFCVHGGISPE-----LKSVEDVNKINRFREIPSRG------- 254

  Fly   395 WQQIFDIMWSDP--------------QATMGCVPNTLRGAGVWFGPDVTDNFLQRHRLSYVIRSH 445
              .:.|::|:||              |:....|||:|||....|....:..||:.:.|..:||:|
Yeast   255 --LMCDLLWADPVENYDDARDGSEFDQSEDEFVPNSLRGCSFAFTFKASCKFLKANGLLSIIRAH 317

  Fly   446 ECKPNGHEFMHDNKI------ITIFSASNYYAIGSNKGAYIRLNNQLM--------PH------- 489
            |.:..|:....:||:      ||:|||.||.....||.|.::....:|        ||
Yeast   318 EAQDAGYRMYKNNKVTGFPSLITMFSAPNYLDTYHNKAAVLKYEENVMNIRQFHMSPHPYWLPDF 382

  Fly   490 ---------FV-----------------QYISAASQTKRL--SFKQRMGIVESSALKELAVRMRD 526
                     ||                 |.:...|:.|..  :.|.|     ::|.||......:
Yeast   383 MDVFTWSLPFVGEKVTSMLVSILNICSEQELDPESEPKAAEETVKAR-----ANATKETGTPSDE 442

  Fly   527 HRDE--LEDEFRKYDPKDSGYISISHWCKVMEN----VTKLGLPWRLLRDKLAPGTDSQKVNYNR 585
            ....  ||||.|:               |.:.|    :.|:...:.:||:      :|:||.|.:
Yeast   443 KASSAILEDETRR---------------KALRNKILAIAKVSRMFSVLRE------ESEKVEYLK 486

  Fly   586 TLDLLDTDVILEAEADGMSVMDALYANKASLVAIFNIIDADNSGEITLDEFETA--IDLLVAHMP 648
            |::.            |:....||......|             ..||..||.|  .||:...:|
Yeast   487 TMNA------------GVLPRGALARGTEGL-------------NETLSTFEKARKEDLINEKLP 526

  Fly   649 GAYSKAEMLEKCRMMD--LNGDGK 670
            .:.|:.|. ||.:..:  |.|..|
Yeast   527 PSLSEVEQ-EKIKYYEKILKGAEK 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rdgC	NP_536738.3	IQ	89..111	CDD:197470
		MPP_RdgC	184..494	CDD:277364	101/391 (26%)
		FRQ1	527..681	CDD:444056	34/154 (22%)
		EFh	616..681	CDD:238008	16/59 (27%)
CNA1	NP_013537.1	MPP_PP2B	70..381	CDD:277361	92/339 (27%)