DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rdgC and AT5G10900

DIOPT Version :9

Sequence 1:	NP_536738.3	Gene:	rdgC / 40224	FlyBaseID:	FBgn0265959	Length:	746	Species:	Drosophila melanogaster
Sequence 2:	NP_001331691.1	Gene:	AT5G10900 / 830957	AraportID:	AT5G10900	Length:	627	Species:	Arabidopsis thaliana

Alignment Length:	648	Identity:	157/648 - (24%)
Similarity:	261/648 - (40%)	Gaps:	145/648 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 CKHFRKPLRGMSASRAE--KTIRAAIFIQKWYRRHQARREMQRRCN----------WQIFQNLEY 124
            ||.....|..:..:|.:  |.:|..:.:::..||...|..::...|          .|:..|.:.
plant    18 CKFAFLKLSAVKTTRMKNYKQLRTLLMLKEISRRGADRDFLKDPENSVTRILCSVLKQVVSNSDR 82

  Fly   125 ASEQDQAELYKFFND--------LIKHMPQAAGRKNQYQGSAHVSVLDDKDDLVE---------- 171
            :.:..:...|:..:|        :|..:.....||.:.:...|   |:|..:.:|
plant    83 SLKSLRGFQYETLDDQEKQQVTRMIASVQGMGSRKYEPETVDH---LEDMTEPIEMEIYLGNGDG 144

  Fly   172 -EFGDIVNAKIELPIRK----NHIDLLIDVFRKKRGNR-------LHPKYVALILREAAKSL--K 222
             :|||||...|..|:..    ..::.|:.:..:.....       :.|..||:.|.:.|..:  |
plant   145 GDFGDIVLEPISWPLESQLTLEWVETLMGLLNQSTWKNSVSEFSLILPHSVAVSLVDCASQILEK 209

  Fly   223 QLPNISPVSTAVSQQVTVCGDLHGKLDDLLVVLHKNGLPSSSNPYVFNGDFVDRGKRGLEVLLLL 287
            :...:.....:...:|.|.|||||:|.|||.:..::|.||.:..:||||:::.||...|||.|:|
plant   210 EANCVKINGCSEDSRVIVVGDLHGQLHDLLKIFDQSGRPSQNQCFVFNGNYIGRGSWSLEVFLVL 274

  Fly   288 LSLYLAFPNAVFLNRGNHEDSVMNARYGFIREVESKYPRNHKRILAFIDEVYRWLPLGSVLNSRV 352
            |:..:..|..|.|.||:.|..|......|::::..:|..:...:.:...:.::.|||.||:::.|
plant   275 LAWKIMMPENVILLRGSSETRVSAEELDFLKDICDRYGEHGPMLYSKCIDCFKMLPLASVISNSV 339

  Fly   353 LIVHGGFSDSTSLDLIKSIDRGKYVSILRPPLTDG--EPLDKTEWQQ----------IFDIMWSD 405
            ...|||...|.          |.:.....|.|..|  |.|||.|.:|          :..::||.
plant   340 YTTHGGLFQSC----------GVHEESPNPSLLLGSLEELDKIERRQAGENDDENITLNHVLWSC 394

  Fly   406 PQATMGCVPNTLRGAGVWFGPDVTDNFLQRHRLSYVIRSHECKP------------NGHEFMHD- 457
            |....|...:..:|. :| |.|.|:.|||:..|..:|||||...            :|:...|:
plant   395 PWMADGLSESNYKGL-LW-GADCTETFLQQSNLKMIIRSHEGPDARADREDMGNMLSGYSIDHEV 457

  Fly   458 --NKIITIFSAS-------NYYAIGSNKGAYIRLN--NQLMPHFVQYISAASQTKRLSFKQRMGI 511
              .|:.|:||||       ||    .|:|||..|.  |...|.||.|  ......||   |...|
plant   458 ESGKLCTVFSASMFSQGSRNY----ENEGAYAVLEPPNFTEPVFVSY--TVENVPRL---QHQII 513

  Fly   512 VESSALKELAVRMRDHRDELEDEFRKYDPKDSGYISIS-----HWCKVMEN----VTKL------ 561
            .:.|:.::  .:|.::|            ...|:.|:.     .|...:.|    :.:|
plant   514 SDGSSTQQ--QQMWENR------------TGHGFASMGISNPPSWTVPLPNDPSQILQLREPPQV 564

  Fly   562 --GLPWRLLRDKLAPGTDSQKVNYN---RTLDLLDTDVILEAEADGMSVMDALYANKASLVAI 619
              |||   |.|.:   .:..|.||:   |.:..|..::......: ..:||.|...||:|..|
plant   565 FEGLP---LPDNI---QEPHKSNYDYLFRLISALKQEIQTRDNRE-KELMDHLTKTKATLEVI 620

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rdgC	NP_536738.3	IQ	89..111	CDD:197470	5/21 (24%)
		MPP_RdgC	184..494	CDD:277364	100/358 (28%)
		EFh	616..681	CDD:238008	2/4 (50%)
AT5G10900	NP_001331691.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910