DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rdgC and Ppp6c

DIOPT Version :9

Sequence 1:	NP_536738.3	Gene:	rdgC / 40224	FlyBaseID:	FBgn0265959	Length:	746	Species:	Drosophila melanogaster
Sequence 2:	NP_077171.1	Gene:	Ppp6c / 67857	MGIID:	1915107	Length:	305	Species:	Mus musculus

Alignment Length:	296	Identity:	99/296 - (33%)
Similarity:	145/296 - (48%)	Gaps:	65/296 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   208 KYVALILREAAKSLKQLP-------------------NISPVSTAVSQQVTVCGDLHGKLDDLLV 253
            |||     |.|:..|.||                   |:.||||    .||||||:||:..||..
Mouse     8 KYV-----EIARQCKYLPENDLKRLCDYVCDLLLEESNVQPVST----PVTVCGDIHGQFYDLCE 63

  Fly   254 VLHKNGLPSSSNPYVFNGDFVDRGKRGLEVLLLLLSLYLAFPNAVFLNRGNHEDSVMNARYGFIR 318
            :....|....:| |:|.|||||||...||....||:|...:|:.:.|.|||||...:...|||..
Mouse    64 LFRTGGQVPDTN-YIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYD 127

  Fly   319 EVESKYPRNHKRILAFIDEVYRWLPLGSVLNSRVLIVHGGFS-DSTSLDLIKSIDRGKYVSILRP 382
            |.::||  .:.....:..:|:..|.:.::::.::|.||||.| |..:||.|::|:|.
Mouse   128 ECQTKY--GNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERN-------- 182

  Fly   383 PLTDGEPLDKTEWQQI------FDIMWSDPQ--ATMGCVPNTLRGAGVWFGPDVTDNFLQRHRLS 439
                         |:|      .|::||||:  .|....|   ||||..||..||:.|:..:.|.
Mouse   183 -------------QEIPHKGAFCDLVWSDPEDVDTWAISP---RGAGWLFGAKVTNEFVHINNLK 231

  Fly   440 YVIRSHECKPNGHEFMHDNKIITIFSASNY-YAIGS 474
            .:.|:|:....|::||.|.|::|::||.|| |..|:
Mouse   232 LICRAHQLVHEGYKFMFDEKLVTVWSAPNYCYRCGN 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rdgC	NP_536738.3	IQ	89..111	CDD:197470
		MPP_RdgC	184..494	CDD:277364	99/296 (33%)
		EFh	616..681	CDD:238008
Ppp6c	NP_077171.1	MPP_PP2A_PP4_PP6	5..289	CDD:277360	99/296 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000