DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rdgC and Ppp5c

DIOPT Version :9

Sequence 1:	NP_536738.3	Gene:	rdgC / 40224	FlyBaseID:	FBgn0265959	Length:	746	Species:	Drosophila melanogaster
Sequence 2:	XP_006228527.2	Gene:	Ppp5c / 65179	RGDID:	68415	Length:	594	Species:	Rattus norvegicus

Alignment Length:	427	Identity:	146/427 - (34%)
Similarity:	208/427 - (48%)	Gaps:	79/427 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 IQKWYRRHQARREMQRRCNWQIFQN-----------LEYASEQDQAELYKFFNDLIKHMPQAAGR 150
            :.:||:   .::::.|:|.:||...           :|...::.:..|:.....:|| ..||.||
  Rat   194 LMQWYK---DQKKLHRKCAYQILVQVKEVLCKLSTLVETTLKEVRLGLWVQGGGVIK-AGQAVGR 254

  Fly   151 KNQYQ---GSAHVSVLDDKDDLVEEFGDIVNAKIELPIRKNHIDLLIDVFRKKRGNRLHPKYVAL 212
            ....:   ...|.|:|...|          .....||     ..||..:          |..:|.
  Rat   255 SPSSRLRNPPVHPSLLSVPD----------TPPTCLP-----SSLLCPL----------PLCLAW 294

  Fly   213 ILREAAKSLKQLPNISPVSTAVS-------------QQVTVCGDLHGKLDDLLVVLHKNGLPSSS 264
            |..... .|..|..:.|:.|::|             :::|||||.||:..|||.:...|||||.:
  Rat   295 IFLVCC-DLSPLIPLCPLPTSLSGPLPLRWPLFFQTEKITVCGDTHGQFYDLLNIFELNGLPSET 358

  Fly   265 NPYVFNGDFVDRGKRGLEVLLLLLSLYLAFPNAVFLNRGNHEDSVMNARYGFIREVESKYPRNHK 329
            |||:|||||||||...:||:|.|....|.:|:...|.|||||...||..|||..||::||.   .
  Rat   359 NPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYT---A 420

  Fly   330 RILAFIDEVYRWLPLGSVLNSRVLIVHGG-FS-DSTSLDLIKSIDRGKYVSILRPPLTDGEPLDK 392
            ::.....||:.||||...:|.:|||:||| || |..:||.|:.|:|.:     :||  |..|:
  Rat   421 QMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNR-----QPP--DSGPM-- 476

  Fly   393 TEWQQIFDIMWSDPQATMGCVPNTLRGAGVWFGPDVTDNFLQRHRLSYVIRSHECKPNGHEFMHD 457
                  .|::|||||...|...:. ||....||||||..||:.::|.|:|||||.|..|:|..|.
  Rat   477 ------CDLLWSDPQPQNGRSVSK-RGVSCQFGPDVTKAFLEENQLDYIIRSHEVKAEGYEVAHG 534

  Fly   458 NKIITIFSASNYYAIGSNKGAYIRL-NNQLMPHFVQY 493
            .:.:|:|||.||.....||.:||.| .:.|.|.|.|:
  Rat   535 GRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQF 571

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rdgC	NP_536738.3	IQ	89..111	CDD:197470	2/13 (15%)
		MPP_RdgC	184..494	CDD:277364	127/326 (39%)
		EFh	616..681	CDD:238008
Ppp5c	XP_006228527.2	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D215218at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920