DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment rdgC and Ppp4c

DIOPT Version :9

Sequence 1:	NP_536738.3	Gene:	rdgC / 40224	FlyBaseID:	FBgn0265959	Length:	746	Species:	Drosophila melanogaster
Sequence 2:	NP_001347393.1	Gene:	Ppp4c / 56420	MGIID:	1891763	Length:	307	Species:	Mus musculus

Alignment Length:	319	Identity:	100/319 - (31%)
Similarity:	163/319 - (51%)	Gaps:	26/319 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   191 DLLIDVFRKKRGNRLHPKYVALILREAAKSLKQLPNISPVSTAVSQQVTVCGDLHGKLDDLLVVL 255
            ||...:.:.:|...:....|..:..:|.:.|.:..|:.    .|...||||||:||:..||..:.
Mouse     6 DLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQ----RVDSPVTVCGDIHGQFYDLKELF 66

  Fly   256 HKNGLPSSSNPYVFNGDFVDRGKRGLEVLLLLLSLYLAFPNAVFLNRGNHEDSVMNARYGFIREV 320
            ...|....:| |:|.|||||||...:|..||||:|.:.:|:.:.|.|||||...:...|||..|.
Mouse    67 RVGGDVPETN-YLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDEC 130

  Fly   321 ESKYPRNHKRILAFIDEVYRWLPLGSVLNSRVLIVHGGFSDS-TSLDLIKSIDRGKYVSILRPPL 384
            ..||  ....:..:..|::.:|.|.::::.::..||||.|.| .:||.|::|||.:.|.
Mouse   131 LRKY--GSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVP------ 187

  Fly   385 TDGEPLDKTEWQQIFDIMWSDPQATMGCVPNTLRGAGVWFGPDVTDNFLQRHRLSYVIRSHECKP 449
            .||         .:.|::||||:.|.|...:. ||||..||.||...|...:.:..:.|:|:...
Mouse   188 HDG---------PMCDLLWSDPEDTTGWGVSP-RGAGYLFGSDVVAQFNAANDIDMICRAHQLVM 242

  Fly   450 NGHEFMHDNKIITIFSASNY-YAIGSNKGAYIRLNNQLMPHFVQYISAASQTKRLSFKQ 507
            .|:::..:..::|::||.|| |..| |..|.:.|:..|...|:.:.:|..:|:.:..|:
Mouse   243 EGYKWHFNETVLTVWSAPNYCYRCG-NVAAILELDEHLQKDFIIFEAAPQETRGIPSKK 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rdgC	NP_536738.3	IQ	89..111	CDD:197470
		MPP_RdgC	184..494	CDD:277364	97/304 (32%)
		EFh	616..681	CDD:238008
Ppp4c	NP_001347393.1	MPP_PP2A_PP4_PP6	6..290	CDD:277360	97/307 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910