DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rdgC and ppp4cb

DIOPT Version :9

Sequence 1:	NP_536738.3	Gene:	rdgC / 40224	FlyBaseID:	FBgn0265959	Length:	746	Species:	Drosophila melanogaster
Sequence 2:	NP_001104638.1	Gene:	ppp4cb / 562705	ZFINID:	ZDB-GENE-080219-32	Length:	307	Species:	Danio rerio

Alignment Length:	320	Identity:	102/320 - (31%)
Similarity:	163/320 - (50%)	Gaps:	28/320 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   190 IDLLIDVFRKKRGNRLHPKYVALILREAAKSLKQLPNISPVSTAVSQQVTVCGDLHGKLDDLLVV 254
            :|..||..|  |...:....|..:..:|.:.|.:..|:.    .|...||||||:||:..||..:
Zfish     7 LDRQIDQLR--RCELIKENEVKALCAKAREILVEESNVQ----RVDSPVTVCGDIHGQFYDLKEL 65

  Fly   255 LHKNGLPSSSNPYVFNGDFVDRGKRGLEVLLLLLSLYLAFPNAVFLNRGNHEDSVMNARYGFIRE 319
            ....|....:| |:|.|||||||...:|..||||:|.:.:|:.:.|.|||||...:...|||..|
Zfish    66 FRVGGDVPETN-YLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDE 129

  Fly   320 VESKYPRNHKRILAFIDEVYRWLPLGSVLNSRVLIVHGGFSDS-TSLDLIKSIDRGKYVSILRPP 383
            ...||  ....:..:..|::.:|.|.::::.::..||||.|.| .:||.|::|||.:.|.
Zfish   130 CLRKY--GSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVP----- 187

  Fly   384 LTDGEPLDKTEWQQIFDIMWSDPQATMGCVPNTLRGAGVWFGPDVTDNFLQRHRLSYVIRSHECK 448
             .||         .:.|::||||:.|.|...:. ||||..||.||...|...:.:..:.|:|:..
Zfish   188 -HDG---------PMCDLLWSDPEDTTGWGVSP-RGAGYLFGSDVVAQFNAANDIDMICRAHQLV 241

  Fly   449 PNGHEFMHDNKIITIFSASNY-YAIGSNKGAYIRLNNQLMPHFVQYISAASQTKRLSFKQ 507
            ..|:::..:..::|::||.|| |..| |..|.:.|:..|...|:.:.:|..:|:.:..|:
Zfish   242 MEGYKWHFNETVLTVWSAPNYCYRCG-NVAAILELDEHLQKEFIIFEAAPQETRGIPSKK 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rdgC	NP_536738.3	IQ	89..111	CDD:197470
		MPP_RdgC	184..494	CDD:277364	99/305 (32%)
		EFh	616..681	CDD:238008
ppp4cb	NP_001104638.1	MPP_PP2A_PP4_PP6	6..290	CDD:277360	99/308 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910