DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment rdgC and PpD6

DIOPT Version :9

Sequence 1:	NP_536738.3	Gene:	rdgC / 40224	FlyBaseID:	FBgn0265959	Length:	746	Species:	Drosophila melanogaster
Sequence 2:	NP_524947.1	Gene:	PpD6 / 49780	FlyBaseID:	FBgn0005779	Length:	336	Species:	Drosophila melanogaster

Alignment Length:	321	Identity:	104/321 - (32%)
Similarity:	161/321 - (50%)	Gaps:	34/321 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   178 NAKIELPIRKNHIDLL--IDVFRKKRGNRLHPKYVALILREAAKSL-----KQLPNISPVSTAVS 235
            ||...||...|..|||  :..||:.:..||.       |.|:..:|     ::|....|:...|.
  Fly    21 NADYRLPGALNLNDLLNKLMSFRRSKMQRLP-------LLESEVNLLCTLARELFLDEPMLLNVP 78

  Fly   236 QQVTVCGDLHGKLDDLLVVLHKNGLPSSSNPYVFNGDFVDRGKRGLEVLLLLLSLYLAFPNAVFL 300
            ..:.|.||:||:..|||.:|.:.|.|..:. |:|.||:|||||..:|.:.|||:|.:.||..::|
  Fly    79 APIRVVGDIHGQFYDLLKILDQCGYPPQTR-YLFLGDYVDRGKNSVETITLLLALRVKFPKHIYL 142

  Fly   301 NRGNHEDSVMNARYGFIREVESKYPRNHKRILAFIDEVYRWLPLGSVLNSRVLIVHGGFSDS-TS 364
            .|||||...:|..|||..|.:.:|  ..|....|:| .|..:|:.::::.|:...|||.|.. ..
  Fly   143 LRGNHESQSVNRVYGFFDECKRRY--TVKLWKTFVD-CYNCMPVAAIISHRIFCCHGGLSPQLKE 204

  Fly   365 LDLIKSIDRGKYVSILRPPLTDGEPLDKTEWQQIFDIMWSDPQATMGCVPNTLRGAGVWFGPDVT 429
            |..|:||.|               |.:..|...:.|::||||........::.||....:|.||.
  Fly   205 LSNIESIAR---------------PTEVPETGLLCDLLWSDPDRYGFGWTSSDRGVSYLYGRDVL 254

  Fly   430 DNFLQRHRLSYVIRSHECKPNGHEFMHDNKIITIFSASNYYAIGSNKGAYIRLNNQLMPHF 490
            :.|||::....|.|:|:...:|:||....:::|:|||.||..:..|.||.:.::..|:..|
  Fly   255 EKFLQKNDFDLVCRAHQVVEDGYEFFAKRQLVTVFSAPNYCGLYDNAGASMGVDKDLVISF 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rdgC	NP_536738.3	IQ	89..111	CDD:197470
		MPP_RdgC	184..494	CDD:277364	101/315 (32%)
		EFh	616..681	CDD:238008
PpD6	NP_524947.1	MPP_superfamily	51..317	CDD:301300	92/291 (32%)
PpD6	NP_524947.1	PP2Ac	54..315	CDD:197547	90/279 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438799
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.840