DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rdgC and PpN58A

DIOPT Version :9

Sequence 1:	NP_536738.3	Gene:	rdgC / 40224	FlyBaseID:	FBgn0265959	Length:	746	Species:	Drosophila melanogaster
Sequence 2:	NP_477384.1	Gene:	PpN58A / 37493	FlyBaseID:	FBgn0025573	Length:	324	Species:	Drosophila melanogaster

Alignment Length:	370	Identity:	113/370 - (30%)
Similarity:	165/370 - (44%)	Gaps:	55/370 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   140 LIKHMPQAAGRKN---QYQGSAHVSVLDDKDDLVEEFGDIVNAKIELPIRKNHIDLLIDVFRKKR 201
            ::|.:......||   ::....::..:..|..|:.|.|.:|...:.
  Fly     1 MMKKLLSNGSNKNKTLKFDEGINLDQIIAKLKLIGEIGSVVQISVR------------------- 46

  Fly   202 GNRLHPKYVALILREAAKSLKQLPNISPVSTAVSQQVTVCGDLHGKLDDLLVVLHKNGLPSSSNP 266
                  :..|:..|.....|||     |....:...:.:.||:||:..:||.....||.|..| .
  Fly    47 ------EIEAVCSRAREVLLKQ-----PTLLEIPAPINLLGDIHGQYLNLLRYFESNGYPPDS-V 99

  Fly   267 YVFNGDFVDRGKRGLEVLLLLLSLYLAFPNAVFLNRGNHEDSVMNARYGFIREVESKYPRNHKRI 331
            |:..||:|||||:.:|.|.|||:|...:|...:|.|||||.|.:|..|||..|.:.:|  ..|..
  Fly   100 YLLLGDYVDRGKQSIETLTLLLALKARYPTKFYLLRGNHECSSINHFYGFYDECKRRY--TVKLW 162

  Fly   332 LAFIDEVYRWLPLGSVLNSRVLIVHGGFSDST-SLDLIKSIDRGKYVSILRPPLTDGEPLDKTEW 395
            ..|:| .|..|||.:::...:...|||.|... |:..|:.|.|               |::..|.
  Fly   163 RTFVD-CYNCLPLAAIIEENIFCCHGGLSPHLFSMQQIREIRR---------------PIEIPES 211

  Fly   396 QQIFDIMWSDPQ-ATMGCVPNTLRGAGVWFGPDVTDNFLQRHRLSYVIRSHECKPNGHEFMHDNK 459
            ..|.||:||||. ..||..||. ||....||.||...||.|.:|:.:.|.|:...:|:||....:
  Fly   212 GLICDILWSDPDLRIMGWGPNE-RGVSHTFGSDVVSAFLHRFKLNLICRGHQVVEDGYEFFAKRQ 275

  Fly   460 IITIFSASNYYAIGSNKGAYIRLNNQLMPHFVQYISAASQTKRLS 504
            :||||||.||.....|.||.:.:|..|:..|.......|:.:|||
  Fly   276 LITIFSAPNYCGEFDNAGAMMCINQDLLCTFRVQRPILSEQRRLS 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rdgC	NP_536738.3	IQ	89..111	CDD:197470
		MPP_RdgC	184..494	CDD:277364	101/311 (32%)
		EFh	616..681	CDD:238008
PpN58A	NP_477384.1	PTZ00480	22..311	CDD:185658	106/338 (31%)
PpN58A	NP_477384.1	MPP_superfamily	23..311	CDD:301300	106/337 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438798
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.930