DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rdgC and Y71G12B.30

DIOPT Version :9

Sequence 1:	NP_536738.3	Gene:	rdgC / 40224	FlyBaseID:	FBgn0265959	Length:	746	Species:	Drosophila melanogaster
Sequence 2:	NP_001021823.2	Gene:	Y71G12B.30 / 3565302	WormBaseID:	WBGene00044347	Length:	333	Species:	Caenorhabditis elegans

Alignment Length:	311	Identity:	90/311 - (28%)
Similarity:	146/311 - (46%)	Gaps:	52/311 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   202 GNRLHPKYVALILR----------EAAKSLKQLPNI----------SPVSTAVSQQVTVCGDLHG 246
            |:.||.|...:|.|          :.....|::..|          .|:...:...||:|||:||
Worm     9 GSPLHRKLTNVIFRLTQSWSPGNCQTLFQEKEIIEICYRAREAFWKEPMKLEIEAPVTICGDIHG 73

  Fly   247 KLDDLLVVLHKNGLP-----SSSNPYVFNGDFVDRGKRGLEVLLLLLSLYLAFPNAVFLNRGNHE 306
            :.:|||.:....|.|     ..|:.|:|.||::|||...:||:.||.:..|..|..:||.|||||
Worm    74 QFEDLLSMFDIYGFPHVSQKDKSSRYLFLGDYIDRGPFSIEVITLLFAYRLLHPQKMFLLRGNHE 138

  Fly   307 DSVMNARYGFIREVESKYPRNHKRILAFIDEVYRW----LPLGSVLNSRVLIVHGGFS-DSTSLD 366
            ...:|.:|||..|.:.:|.       ..:.|.::|    :||.:::..|::.:|||.. ...||:
Worm   139 SRPVNMQYGFYNECKRRYS-------VTLYETFQWAFYCMPLCAIVGGRIMCMHGGIPFGLLSLE 196

  Fly   367 LIKSIDRGKYVSILRPPLTDGEPLDKTEWQQIFDIMWSDPQATMGCVPNTLRGAGVWFGPDVTDN 431
            .|....|               |.|..:.....|:.|:||.:.:....::.||||..||......
Worm   197 QIDEFQR---------------PTDIADVGIPSDLCWADPVSGVVGFQDSPRGAGHVFGEATVKE 246

  Fly   432 FLQRHRLSYVIRSHECKPNGHEFMHDNKIITIFSASNYYAIGSNKGAYIRL 482
            |.::.:|..::|:|:...:|:||..|.|::|||||..|.....|.||.:::
Worm   247 FNEKFKLDLIVRAHQVVMDGYEFFADKKLVTIFSAPCYCGHFDNLGAVLQV 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rdgC	NP_536738.3	IQ	89..111	CDD:197470
		MPP_RdgC	184..494	CDD:277364	90/311 (29%)
		EFh	616..681	CDD:238008
Y71G12B.30	NP_001021823.2	PP2Ac	36..308	CDD:197547	84/284 (30%)
Y71G12B.30	NP_001021823.2	MPP_superfamily	36..304	CDD:301300	84/284 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.000