DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rdgC and gsp-2

DIOPT Version :9

Sequence 1:	NP_536738.3	Gene:	rdgC / 40224	FlyBaseID:	FBgn0265959	Length:	746	Species:	Drosophila melanogaster
Sequence 2:	NP_001022616.1	Gene:	gsp-2 / 3564807	WormBaseID:	WBGene00001748	Length:	333	Species:	Caenorhabditis elegans

Alignment Length:	324	Identity:	101/324 - (31%)
Similarity:	166/324 - (51%)	Gaps:	27/324 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   183 LPIRKNHIDLLIDVFRKKRGNRLHP-KYVALI---LREAAKSLKQLPNISPVSTAVSQQVTVCGD 243
            :.:.|.::|.:|....:.||::  | |.|.|.   ::...:..:::....|:...:...:.:|||
Worm     1 MDVEKLNLDNIISRLLEVRGSK--PGKNVQLTESEIKGLCQKSREIFLSQPILLELEAPLKICGD 63

  Fly   244 LHGKLDDLLVVLHKNGLPSSSNPYVFNGDFVDRGKRGLEVLLLLLSLYLAFPNAVFLNRGNHEDS 308
            :||:..|||.:....|.|..|| |:|.||:|||||:.||.:.|||:..:.:|...||.|||||.:
Worm    64 VHGQYYDLLRLFEYGGFPPESN-YLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECA 127

  Fly   309 VMNARYGFIREVESKYPRNHKRILAFIDEVYRWLPLGSVLNSRVLIVHGGFS-DSTSLDLIKSID 372
            .:|..|||..|.:.:|  |.|....|.| .:..||:.::::.::...|||.| |..|::.|:.|.
Worm   128 SINRIYGFYDECKRRY--NIKLWKTFTD-CFNCLPVAAIIDEKIFCCHGGLSPDLQSMEQIRRIM 189

  Fly   373 RGKYVSILRPPLTDGEPLDKTEWQQIFDIMWSDPQATMGCVPNTLRGAGVWFGPDVTDNFLQRHR 437
            |               |.|..:...:.|::||||...:.......||....|||:|...||.:|.
Worm   190 R---------------PTDVPDQGLLCDLLWSDPDKDVTGWGENDRGVSFTFGPEVVAKFLHKHD 239

  Fly   438 LSYVIRSHECKPNGHEFMHDNKIITIFSASNYYAIGSNKGAYIRLNNQLMPHFVQYISAASQTK 501
            |..:.|:|:...:|:||....:::|:|||.||.....|.|:.:.::..||..| |.:..|.:.|
Worm   240 LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGSMMTVDETLMCSF-QILKPADKKK 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rdgC	NP_536738.3	IQ	89..111	CDD:197470
		MPP_RdgC	184..494	CDD:277364	99/314 (32%)
		EFh	616..681	CDD:238008
gsp-2	NP_001022616.1	PTZ00480	5..315	CDD:185658	101/320 (32%)
gsp-2	NP_001022616.1	MPP_PP1_PPKL	7..297	CDD:277359	98/311 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910