Protein Alignment rdgC and Ppef1

DIOPT Version :10

• Sequence 1: NP_536738.3
• Gene: rdgC / 40224
• FlyBaseID: FBgn0265959
• Length: 746
• Species: Drosophila melanogaster
• Sequence 2: NP_001421152.1
• Gene: Ppef1 / 317498
• RGDID: 1562772
• Length: 664
• Species: Rattus norvegicus
• Alignment Length: 641
• Identity: 259/641 - (40%)
• Similarity: 384/641 - (59%)
• Gaps: 51/641 - (7%)

  Fly    91 IRAAIFIQKWYRRHQARREMQRRCNWQIFQNLEYASEQDQAELYKFFNDLIKHMPQAAGRKNQYQ 155
            :|||:.||.||||::||...::.....|||::|||.||.|.:|..||:.::::.     .....:
  Rat    41 VRAALIIQNWYRRYRARLSARQHYALAIFQSIEYADEQGQMQLSSFFSFMLENY-----TNTHKE 100

  Fly   156 GSAHVS------VLDDKDDLVEEFGDIVNA-------KIELPIRKNHIDLLIDVFRKKRGNRLHP 207
            .||.||      .|:.||.  ||:..:::.       :::.|:....|:||:..|::::  .||.
  Rat   101 DSALVSRLFENTRLESKDR--EEYVGLIDVPDSYDGPRLQFPLTFTDINLLLQAFKQQQ--TLHA 161

  Fly   208 KYVALILREAAKSLKQLPNISPVSTAVSQQVTVCGDLHGKLDDLLVVLHKNGLPSSSNPYVFNGD 272
            .||..:|.||.|.|||:||.:.:.|..::::|:|||||||||||:::.:||||||..||||||||
  Rat   162 HYVLEVLFEARKILKQMPNFTRIQTFPAKEITICGDLHGKLDDLMLIFYKNGLPSEKNPYVFNGD 226

  Fly   273 FVDRGKRGLEVLLLLLSLYLAFPNAVFLNRGNHEDSVMNARYGFIREVESKYPRNHKRILAFIDE 337
            |||||...:|:|::||..:|.:|..:.||||||||.:||.||||.:|:..||..:.|:||..::|
  Rat   227 FVDRGNNSMEILMILLVSFLVYPTDLHLNRGNHEDFMMNLRYGFTKEILQKYKLHGKKILQVLEE 291

  Fly   338 VYRWLPLGSVLNSRVLIVHGGFSDSTSLDLIKSIDRGKYVSILRPPLTD---------------- 386
            :|.|||:|:::::.:|::|||.|:||.|::::.:.|.|..|:|.||::.
  Rat   292 LYTWLPIGTIIDNEILVIHGGISESTDLNILQQLQRNKMKSVLMPPMSTNQECNIKKNKAGPSEQ 356

  Fly   387 --GEPLDKTEWQQIFDIMWSDPQATMGCVPNTLRGAGVWFGPDVTDNFLQRHRLSYVIRSHECKP 449
              .|.|.|.||:||.|::||||:...||.|||.||.|.:||||||...|.:::|..|||||||||
  Rat   357 SASEQLTKLEWEQIIDLLWSDPRGKKGCYPNTSRGGGCYFGPDVTSKVLNKNQLKMVIRSHECKP 421

  Fly   450 NGHEFMHDNKIITIFSASNYYAIGSNKGAYIRLNNQLMPHFVQYISAASQTKRLS-FKQRMGIVE 513
            :|:|..||.|:||:|||||||..|||:||||||:....|.|.||  ..:.|..|: ..||:..:|
  Rat   422 DGYEICHDGKVITVFSASNYYEEGSNRGAYIRLSYGTSPQFFQY--QVTSTSCLNPLYQRVNAME 484

  Fly   514 SSALKELAVRMRDHRDELEDEFRKYDPKDSGYISISHWCKVMENVTKLGLPWRLLRDKLAPGTDS 578
            .||.:.|..||...:.:|.:.|...|...:|.||::.|...||::..|.||||.|...|.....|
  Rat   485 FSAFRILKERMIARKTDLINAFELRDHSRTGKISLAQWAFSMESILGLNLPWRSLSSHLVSTDSS 549

  Fly   579 QKVNYNRTLDLLDTDVILEAEADGM--SVMDALYANKASLVAIFNIIDADNSGEITLDEFETAID 641
            ..|:|..:.|    |:.:|.....|  .:::.:|..::.|..||||||.|.||.|::|||.|...
  Rat   550 GSVDYMSSFD----DIHIEKPMKDMKSDLIETMYRYRSDLKIIFNIIDTDQSGLISMDEFRTMWK 610

  Fly   642 LLVAHMPGAYSKAEMLEKCRMMDLNGDGKVDLNEFLEAFRLSDLHRKEQQDENIRR 697
            |..||.......:::.|....||.|.||.:|.||||.||.:  :|:.|..:..:.:
  Rat   611 LFNAHYKVHIDDSQIDELASTMDSNKDGNIDFNEFLRAFYV--VHKYETPESPLNK 664

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rdgC	NP_536738.3	IQ	89..111	CDD:197470	11/19 (58%)
		MPP_RdgC	184..494	CDD:277364	159/327 (49%)
		FRQ1	527..681	CDD:444056	54/155 (35%)
		EFh	616..681	CDD:238008	30/64 (47%)
Ppef1	NP_001421152.1	IQ	40..>57	CDD:197470	9/15 (60%)
		MPP_RdgC	140..466	CDD:277364	160/329 (49%)
		FRQ1	498..660	CDD:444056	57/167 (34%)