DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rdgC and Ppp1cb

DIOPT Version :9

Sequence 1:	NP_536738.3	Gene:	rdgC / 40224	FlyBaseID:	FBgn0265959	Length:	746	Species:	Drosophila melanogaster
Sequence 2:	NP_037197.1	Gene:	Ppp1cb / 25594	RGDID:	3376	Length:	327	Species:	Rattus norvegicus

Alignment Length:	307	Identity:	96/307 - (31%)
Similarity:	153/307 - (49%)	Gaps:	26/307 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   189 HIDLLIDVFRKKRGNRLHPKYVALILREAAKSL----KQLPNISPVSTAVSQQVTVCGDLHGKLD 249
            ::|.||....:.||.|  |..:..:.....:.|    :::....|:...:...:.:|||:||:..
  Rat     7 NVDSLITRLLEVRGCR--PGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYT 69

  Fly   250 DLLVVLHKNGLPSSSNPYVFNGDFVDRGKRGLEVLLLLLSLYLAFPNAVFLNRGNHEDSVMNARY 314
            |||.:....|.|..:| |:|.||:|||||:.||.:.|||:..:.:|...||.|||||.:.:|..|
  Rat    70 DLLRLFEYGGFPPEAN-YLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIY 133

  Fly   315 GFIREVESKYPRNHKRILAFIDEVYRWLPLGSVLNSRVLIVHGGFS-DSTSLDLIKSIDRGKYVS 378
            ||..|.:.::  |.|....|.| .:..||:.::::.::...|||.| |..|::.|:.|.|
  Rat   134 GFYDECKRRF--NIKLWKTFTD-CFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMR----- 190

  Fly   379 ILRPPLTDGEPLDKTEWQQIFDIMWSDPQATMGCVPNTLRGAGVWFGPDVTDNFLQRHRLSYVIR 443
                      |.|..:...:.|::||||...:.......||....||.||...||.||.|..:.|
  Rat   191 ----------PTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICR 245

  Fly   444 SHECKPNGHEFMHDNKIITIFSASNYYAIGSNKGAYIRLNNQLMPHF 490
            :|:...:|:||....:::|:|||.||.....|.|..:.::..||..|
  Rat   246 AHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSF 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rdgC	NP_536738.3	IQ	89..111	CDD:197470
		MPP_RdgC	184..494	CDD:277364	96/307 (31%)
		EFh	616..681	CDD:238008
Ppp1cb	NP_037197.1	MPP_PP1_PPKL	7..297	CDD:277359	96/307 (31%)
Ppp1cb	NP_037197.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	305..327
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910