DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rdgC and Ppp1cc

DIOPT Version :9

Sequence 1:	NP_536738.3	Gene:	rdgC / 40224	FlyBaseID:	FBgn0265959	Length:	746	Species:	Drosophila melanogaster
Sequence 2:	NP_001257912.1	Gene:	Ppp1cc / 24669	RGDID:	3377	Length:	337	Species:	Rattus norvegicus

Alignment Length:	326	Identity:	106/326 - (32%)
Similarity:	164/326 - (50%)	Gaps:	35/326 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   185 IRKNHIDLLIDVFRKKRGNR------LHPKYV-ALILREAAKSLKQLPNISPVSTAVSQQVTVCG 242
            |.|.:||.:|....:.||::      |....: .|.|:.....|.|     |:...:...:.:||
  Rat     4 IDKLNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQ-----PILLELEAPLKICG 63

  Fly   243 DLHGKLDDLLVVLHKNGLPSSSNPYVFNGDFVDRGKRGLEVLLLLLSLYLAFPNAVFLNRGNHED 307
            |:||:..|||.:....|.|..|| |:|.||:|||||:.||.:.|||:..:.:|...||.|||||.
  Rat    64 DIHGQYYDLLRLFEYGGFPPESN-YLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHEC 127

  Fly   308 SVMNARYGFIREVESKYPRNHKRILAFIDEVYRWLPLGSVLNSRVLIVHGGFS-DSTSLDLIKSI 371
            :.:|..|||..|.:.:|  |.|....|.| .:..||:.::::.::...|||.| |..|::.|:.|
  Rat   128 ASINRIYGFYDECKRRY--NIKLWKTFTD-CFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRI 189

  Fly   372 DRGKYVSILRPPLTDGEPLDKTEWQQIFDIMWSDP-QATMGCVPNTLRGAGVWFGPDVTDNFLQR 435
            .|               |.|..:...:.|::|||| :..:|...|. ||....||.:|...||.:
  Rat   190 MR---------------PTDVPDQGLLCDLLWSDPDKDVLGWGEND-RGVSFTFGAEVVAKFLHK 238

  Fly   436 HRLSYVIRSHECKPNGHEFMHDNKIITIFSASNYYAIGSNKGAYIRLNNQLMPHFVQYISAASQT 500
            |.|..:.|:|:...:|:||....:::|:|||.||.....|.||.:.::..||..| |.:..|.:.
  Rat   239 HDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSF-QILKPAEKK 302

  Fly   501 K 501
            |
  Rat   303 K 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rdgC	NP_536738.3	IQ	89..111	CDD:197470
		MPP_RdgC	184..494	CDD:277364	104/317 (33%)
		EFh	616..681	CDD:238008
Ppp1cc	NP_001257912.1	MPP_PP1_PPKL	8..298	CDD:277359	102/315 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910