DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rdgC and ZK938.1

DIOPT Version :9

Sequence 1:	NP_536738.3	Gene:	rdgC / 40224	FlyBaseID:	FBgn0265959	Length:	746	Species:	Drosophila melanogaster
Sequence 2:	NP_496117.1	Gene:	ZK938.1 / 191467	WormBaseID:	WBGene00014158	Length:	327	Species:	Caenorhabditis elegans

Alignment Length:	353	Identity:	92/353 - (26%)
Similarity:	163/353 - (46%)	Gaps:	58/353 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   181 IELPIRKNHIDLLIDVFRKKRGNRLHPKYVALILREA-----AKSLKQLPNISPVSTAVSQQVTV 240
            :.:|   |.||.::.|......:..|      .::||     .:..|.:.:.......|...:.|
Worm     2 VNIP---NFIDKVLSVNDTSNASLTH------CIKEADIDGVIEECKDILSAQATMVEVQAPIAV 57

  Fly   241 CGDLHGKLDDLLVVLHKNGLPSSSNPYVFNGDFVDRGKRGLEVLLLLLSLYLAFPNAVFLNRGNH 305
            |||:||:..|||.:.::...|...| |:|.||:||||::.|||:.||::..:.:||..|:.||||
Worm    58 CGDIHGQYTDLLRIFNRCSFPPDQN-YLFLGDYVDRGRQQLEVICLLMAYKVRYPNGFFILRGNH 121

  Fly   306 EDSVMNARYGFIREVESKYPRNHKRILAFIDE---VYRWLPLGSVLNSRVLIVHGGFSDSTSLDL 367
            |.:.:|..|||..|.:.:|.      ||..:|   ::..|||.::::.|:..:|||.|.    :|
Worm   122 ECASINRTYGFYDECKRRYS------LALYNEFQNLFNSLPLCAMISGRIFCMHGGLSP----EL 176

  Fly   368 IKSIDRGKYVSILRPPLTDGEPLDKTEWQQIFDIMWSDPQATMGCVPNTLRGAGVWFGPDVTDNF 432
            :......|.:          .|.|........|::|:||:..........||....||.:|..:|
Worm   177 VSWTQLAKII----------RPFDPPNACLAMDLLWADPENNHTGWGKNSRGVSYIFGANVVKDF 231

  Fly   433 LQRHRLSYVIRSHECKPNGHEFMHDNKIITIFSASNYYAIGSNKGAYIRLNNQLMPHFVQYISAA 497
            .::..:..:.|.|:...:|:||..|.:::|||||..|.....|....:.::.:|:
Worm   232 TEKMNIDLIARGHQVVQDGYEFFADKRLVTIFSAPKYCGEFDNNAGIMIVDERLI---------- 286

  Fly   498 SQTKRLSFKQRMGIVESSALKELAVRMR 525
                 :||:     :...|::|:.::.|
Worm   287 -----ISFE-----ILKPAMREVKIQAR 304

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rdgC	NP_536738.3	IQ	89..111	CDD:197470
		MPP_RdgC	184..494	CDD:277364	87/317 (27%)
		EFh	616..681	CDD:238008
ZK938.1	NP_496117.1	MPP_superfamily	3..294	CDD:301300	89/340 (26%)
ZK938.1	NP_496117.1	PP2Ac	28..296	CDD:197547	83/308 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.000