DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment rdgC and ZK354.9

DIOPT Version :9

Sequence 1:	NP_536738.3	Gene:	rdgC / 40224	FlyBaseID:	FBgn0265959	Length:	746	Species:	Drosophila melanogaster
Sequence 2:	NP_500776.2	Gene:	ZK354.9 / 191296	WormBaseID:	WBGene00022710	Length:	296	Species:	Caenorhabditis elegans

Alignment Length:	294	Identity:	99/294 - (33%)
Similarity:	153/294 - (52%)	Gaps:	23/294 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   204 RLHPKYVALILREAAKSLKQ-----LPNISPVSTAVSQQVTVCGDLHGKLDDLLVVLHKNGLPSS 263
            :|..:.|.|..|...:||::     :.|..|:....:..:.:|||:||:..|||.:..|||.|..
Worm     2 KLRRRVVCLRARARPQSLRRRRTCNIFNKQPMLIEANSPINICGDIHGQFSDLLRLFDKNGFPHR 66

  Fly   264 SNPYVFNGDFVDRGKRGLEVLLLLLSLYLAFPNAVFLNRGNHEDSVMNARYGFIREVESKYPRNH 328
            :| |:|.||:|||||..||.:|||.:..:.|||..|:.|||||.|::|..|||..|.:.:|  |.
Worm    67 AN-YLFLGDYVDRGKHCLETILLLFAYKVIFPNHFFMLRGNHECSLINKIYGFYDECQRRY--NK 128

  Fly   329 KRILAFIDEVYRWLPLGSVLNSRVLIVHGGFSDSTSLDLIKSIDRGKYVSILRPPLTDGEPLDKT 393
            ..:....:.|:..:||.:::..|:|.:|||.|        |.:.....:..::.|..:.||....
Worm   129 PSVYVSFEGVFSDMPLTALVGQRILCMHGGVS--------KMLQNVSQLRAIKRPFDNPEPNTLA 185

  Fly   394 EWQQIFDIMWSDP-QATMGCVPNTLRGAGVWFGPDVTDNFLQRHRLSYVIRSHECKPNGHEFMHD 457
                 .||:|||| ....|..||: ||....||.|.....|.|.::..|:|:|:...:|:||..:
Worm   186 -----IDILWSDPTNFQKGWNPNS-RGVSYVFGSDALRKLLDRLQIDLVVRAHQVVQDGYEFFAN 244

  Fly   458 NKIITIFSASNYYAIGSNKGAYIRLNNQLMPHFV 491
            .:::|||||..|.....|..|.:.:|..|:..||
Worm   245 RRLVTIFSAPFYCGQFDNAAAVMYVNKNLVCSFV 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rdgC	NP_536738.3	IQ	89..111	CDD:197470
		MPP_RdgC	184..494	CDD:277364	99/294 (34%)
		EFh	616..681	CDD:238008
ZK354.9	NP_500776.2	MPP_superfamily	6..282	CDD:301300	98/290 (34%)
ZK354.9	NP_500776.2	PP2Ac	22..284	CDD:197547	93/274 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3051
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.860