DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rdgC and Y69E1A.4

DIOPT Version :9

Sequence 1:	NP_536738.3	Gene:	rdgC / 40224	FlyBaseID:	FBgn0265959	Length:	746	Species:	Drosophila melanogaster
Sequence 2:	NP_502041.1	Gene:	Y69E1A.4 / 190550	WormBaseID:	WBGene00013476	Length:	375	Species:	Caenorhabditis elegans

Alignment Length:	353	Identity:	96/353 - (27%)
Similarity:	151/353 - (42%)	Gaps:	73/353 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   209 YVALILREAAKSLKQLPNISPVSTAVSQQVTVCGDLHGKLDDLLVVLHKNGLPSSSNP------- 266
            :.|..|.|.....::|....|:...:...:.|.||:||:.||||.:|..||.|.||..
Worm    36 FCAAELAELCHRARELIWSEPIFLKLEAPICVMGDIHGQFDDLLAMLDMNGWPLSSQEFEALKDT 100

  Fly   267 ----------------------------------------------YVFNGDFVDRGKRGLEVLL 285
                                                          |:|.||:||||...:||::
Worm   101 TVRSRETGKRPQSEPHSTQPESSNDVKPPVAAPKSVNKEVTTGYKRYLFLGDYVDRGPFSMEVVI 165

  Fly   286 LLLSLYLAFPNAVFLNRGNHEDSVMNARYGFIREVESKYPRNHKRILAFIDEVYRWLPLGSVLNS 350
            ||.:|.||:|:.::|.|||||...:|..|||.|||..:|   ..::......::...|..:|:|:
Worm   166 LLTALKLAYPDRIYLLRGNHESRSVNTSYGFYREVNYRY---DAQLYECFQNMFNVFPFCAVINN 227

  Fly   351 RVLIVHGGFSDS-TSLDLIKSIDRGKYVSILRPPLTDGEPLDKTEWQQIFDIMWSDPQATMGCVP 414
            .::.:|||.|:. ||.:......|               ||:..:...:.|:.|:||..|.....
Worm   228 TIMCMHGGISEHLTSFNQFSVFKR---------------PLEIPDVGVLTDLTWADPDPTEKGYK 277

  Fly   415 NTLRGAGVWFGPDVTDNFLQRHRLSYVIRSHECKPNGHEFMHDNKIITIFSASNYYAIGSNKGAY 479
            .:.|||...|||.....||::..|..|||.|:...:|:||....:::|||||.||.....|..|.
Worm   278 PSARGASFVFGPPALRAFLKKLDLQMVIRGHQVVEDGYEFFDGRRLVTIFSAPNYCGQNDNTAAV 342

  Fly   480 IRLNNQLMPHFVQYISAASQTKRLSFKQ 507
            ..::.:|... :......|:.|:..|::
Worm   343 FSIDKKLKIS-INVFRPESRDKKRGFEK 369

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rdgC	NP_536738.3	IQ	89..111	CDD:197470
		MPP_RdgC	184..494	CDD:277364	93/338 (28%)
		EFh	616..681	CDD:238008
Y69E1A.4	NP_502041.1	PP2Ac	36..360	CDD:197547	93/342 (27%)
Y69E1A.4	NP_502041.1	MPP_superfamily	39..358	CDD:301300	92/337 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.000