DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rdgC and Ppp1ca

DIOPT Version :9

Sequence 1:	NP_536738.3	Gene:	rdgC / 40224	FlyBaseID:	FBgn0265959	Length:	746	Species:	Drosophila melanogaster
Sequence 2:	NP_114074.1	Gene:	Ppp1ca / 19045	MGIID:	103016	Length:	330	Species:	Mus musculus

Alignment Length:	320	Identity:	102/320 - (31%)
Similarity:	162/320 - (50%)	Gaps:	27/320 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   187 KNHIDLLIDVFRKKRGNRLHP-KYVALI---LREAAKSLKQLPNISPVSTAVSQQVTVCGDLHGK 247
            |.::|.:|....:.:|:|  | |.|.|.   :|......:::....|:...:...:.:|||:||:
Mouse     6 KLNLDSIIGRLLEVQGSR--PGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQ 68

  Fly   248 LDDLLVVLHKNGLPSSSNPYVFNGDFVDRGKRGLEVLLLLLSLYLAFPNAVFLNRGNHEDSVMNA 312
            ..|||.:....|.|..|| |:|.||:|||||:.||.:.|||:..:.:|...||.|||||.:.:|.
Mouse    69 YYDLLRLFEYGGFPPESN-YLFLGDYVDRGKQSLETICLLLAYKIRYPENFFLLRGNHECASINR 132

  Fly   313 RYGFIREVESKYPRNHKRILAFIDEVYRWLPLGSVLNSRVLIVHGGFS-DSTSLDLIKSIDRGKY 376
            .|||..|.:.:|  |.|....|.| .:..||:.::::.::...|||.| |..|::.|:.|.|
Mouse   133 IYGFYDECKRRY--NIKLWKTFTD-CFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMR--- 191

  Fly   377 VSILRPPLTDGEPLDKTEWQQIFDIMWSDPQATMGCVPNTLRGAGVWFGPDVTDNFLQRHRLSYV 441
                        |.|..:...:.|::||||...:.......||....||.:|...||.:|.|..:
Mouse   192 ------------PTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLI 244

  Fly   442 IRSHECKPNGHEFMHDNKIITIFSASNYYAIGSNKGAYIRLNNQLMPHFVQYISAASQTK 501
            .|:|:...:|:||....:::|:|||.||.....|.||.:.::..||..| |.:..|.:.|
Mouse   245 CRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSF-QILKPADKNK 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rdgC	NP_536738.3	IQ	89..111	CDD:197470
		MPP_RdgC	184..494	CDD:277364	100/311 (32%)
		EFh	616..681	CDD:238008
Ppp1ca	NP_114074.1	PTZ00480	6..308	CDD:185658	102/320 (32%)
		MPP_PP1_PPKL	8..298	CDD:277359	99/311 (32%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	306..330
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910