DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rdgC and T25B9.2

DIOPT Version :9

Sequence 1:	NP_536738.3	Gene:	rdgC / 40224	FlyBaseID:	FBgn0265959	Length:	746	Species:	Drosophila melanogaster
Sequence 2:	NP_501992.2	Gene:	T25B9.2 / 188880	WormBaseID:	WBGene00012008	Length:	343	Species:	Caenorhabditis elegans

Alignment Length:	353	Identity:	96/353 - (27%)
Similarity:	151/353 - (42%)	Gaps:	73/353 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   209 YVALILREAAKSLKQLPNISPVSTAVSQQVTVCGDLHGKLDDLLVVLHKNGLPSSSNP------- 266
            :.|..|.|.....::|....|:...:...:.|.||:||:.||||.:|..||.|.||..
Worm     4 FCAAELAELCHRARELIWSEPIFLKLEAPICVMGDIHGQFDDLLAMLDMNGWPLSSQEFEALKDI 68

  Fly   267 ----------------------------------------------YVFNGDFVDRGKRGLEVLL 285
                                                          |:|.||:||||...:||::
Worm    69 TVRSRETGKRPQSEPHSTQPESSNDVKPPVAAPKSVNKEVTTGYKRYLFLGDYVDRGPFSMEVVI 133

  Fly   286 LLLSLYLAFPNAVFLNRGNHEDSVMNARYGFIREVESKYPRNHKRILAFIDEVYRWLPLGSVLNS 350
            ||.:|.||:|:.::|.|||||...:|..|||.|||..:|   ..::......::...|..:|:|:
Worm   134 LLTALKLAYPDRIYLLRGNHESRSVNTSYGFYREVNYRY---DAQLYECFQNMFNVFPFCAVINN 195

  Fly   351 RVLIVHGGFSDS-TSLDLIKSIDRGKYVSILRPPLTDGEPLDKTEWQQIFDIMWSDPQATMGCVP 414
            .::.:|||.|:. ||.:......|               ||:..:...:.|:.|:||..|.....
Worm   196 TIMCMHGGISEHLTSFNQFSVFKR---------------PLEIPDVGVLTDLTWADPDPTEKGYK 245

  Fly   415 NTLRGAGVWFGPDVTDNFLQRHRLSYVIRSHECKPNGHEFMHDNKIITIFSASNYYAIGSNKGAY 479
            .:.|||...|||.....||::..|..|||.|:...:|:||....:::|||||.||.....|..|.
Worm   246 PSARGASFVFGPPALRAFLKKLDLQMVIRGHQVVEDGYEFFDGRRLVTIFSAPNYCGQNDNTAAV 310

  Fly   480 IRLNNQLMPHFVQYISAASQTKRLSFKQ 507
            ..::.:|... :......|:.|:..|::
Worm   311 FSIDKKLKIS-INVFRPESRDKKRGFEK 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rdgC	NP_536738.3	IQ	89..111	CDD:197470
		MPP_RdgC	184..494	CDD:277364	93/338 (28%)
		EFh	616..681	CDD:238008
T25B9.2	NP_501992.2	PP2Ac	4..328	CDD:197547	93/342 (27%)
T25B9.2	NP_501992.2	MPP_superfamily	7..326	CDD:301300	92/337 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.000