DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rdgC and F25B3.4

DIOPT Version :9

Sequence 1:	NP_536738.3	Gene:	rdgC / 40224	FlyBaseID:	FBgn0265959	Length:	746	Species:	Drosophila melanogaster
Sequence 2:	NP_001369922.1	Gene:	F25B3.4 / 184915	WormBaseID:	WBGene00009101	Length:	363	Species:	Caenorhabditis elegans

Alignment Length:	322	Identity:	104/322 - (32%)
Similarity:	162/322 - (50%)	Gaps:	25/322 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   178 NAKIEL-PIRKNHIDLLIDVFRK--KRGNRLHPKYVALILREAAKSLK----QLPNISPVSTAVS 235
            |:|..: |..|:.|.....:..:  :.|.....:...||..|..::|.    .:.|..|:...|:
Worm    41 NSKTAITPENKSMIQFAYSILMRVLESGKSTDMELTRLIPPEDVETLLFHAFSIFNKQPMLIEVN 105

  Fly   236 QQVTVCGDLHGKLDDLLVVLHKNGLPSSSNPYVFNGDFVDRGKRGLEVLLLLLSLYLAFPNAVFL 300
            ..:.:|||:||:..|||.:..|||.|..:| |:|.||:|||||..||.:|||.:..:.|||..|:
Worm   106 SPINICGDIHGQFSDLLRLFDKNGFPHRAN-YLFLGDYVDRGKHCLETILLLFAYKVIFPNHFFM 169

  Fly   301 NRGNHEDSVMNARYGFIREVESKYPRNHKRILAFIDEVYRWLPLGSVLNSRVLIVHGGFSDSTSL 365
            .|||||.|::|.:|||..|.:.:|  |...:......|:..:||.:::..|:|.:|||.|
Worm   170 LRGNHECSLINRQYGFYEECQRRY--NKPSVWHSFQGVFSVMPLTALVGQRILCMHGGVS----- 227

  Fly   366 DLIKSIDRGKYVSILRPPLTDGEPLDKTEWQQIFDIMWSDP-QATMGCVPNTLRGAGVWFGPDVT 429
               |.:.....:..::.|..:.||....     .||:|||| ....|..||: ||....||.|..
Worm   228 ---KMLQNVSQLRAIKRPFDNPEPNTLA-----IDILWSDPTNFQKGWNPNS-RGVSYVFGSDAL 283

  Fly   430 DNFLQRHRLSYVIRSHECKPNGHEFMHDNKIITIFSASNYYAIGSNKGAYIRLNNQLMPHFV 491
            ...|.|.::..|:|:|:...:|:||..:.:::|||||..|.....|..|.:.:|..|:..||
Worm   284 RKLLDRLQIDLVVRAHQVVQDGYEFFANRRLVTIFSAPFYCGQFDNAAAVMYVNKNLVCSFV 345

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rdgC	NP_536738.3	IQ	89..111	CDD:197470
		MPP_RdgC	184..494	CDD:277364	102/315 (32%)
		EFh	616..681	CDD:238008
F25B3.4	NP_001369922.1	PP2Ac	79..351	CDD:197547	97/284 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3051
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.860