DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rdgC and C47A4.3

DIOPT Version :9

Sequence 1:	NP_536738.3	Gene:	rdgC / 40224	FlyBaseID:	FBgn0265959	Length:	746	Species:	Drosophila melanogaster
Sequence 2:	NP_502650.1	Gene:	C47A4.3 / 178340	WormBaseID:	WBGene00008124	Length:	316	Species:	Caenorhabditis elegans

Alignment Length:	317	Identity:	104/317 - (32%)
Similarity:	163/317 - (51%)	Gaps:	35/317 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   185 IRKNHID-LLIDVFRKKRGNRLHPKYVALILREAAKSLKQLPNISPVSTA------VSQQVTVCG 242
            ::.|.:| ::|||....    .|.|.:..::.| .:.||.|.....|..|      |:..:.|||
Worm     1 MQNNVVDSIIIDVLSAS----THEKPLCKVITE-ERVLKLLDLALGVFKAQKPMVEVNAPIKVCG 60

  Fly   243 DLHGKLDDLLVVLHKNGLPSSSNPYVFNGDFVDRGKRGLEVLLLLLSLYLAFPNAVFLNRGNHED 307
            |:||:..|||.:.|:.|.|.::| |:|.||:||||:..:|.::|||:..:.||...||.|||||.
Worm    61 DIHGQFPDLLRLFHRGGWPPTAN-YLFLGDYVDRGRFSIETIVLLLAYKVKFPCNFFLLRGNHEC 124

  Fly   308 SVMNARYGFIREVESKYPRNHKRILAFIDEVYRWLPLGSVLNSRVLIVHGGFS----DSTSLDLI 368
            ..:|..|||..|.:.:|  ...|:.|...:|:.||||..::.:::|.:|||.|    ...:||.:
Worm   125 EFVNKTYGFYEECQKRY--QSVRMYAAFQDVFNWLPLTGLIATKILCMHGGLSPLMTKEFTLDTL 187

  Fly   369 KSIDRGKYVSILRPPLTDGEPLDKTEWQQIFDIMWSDPQATMGCVPNTLRGAGVWFGPDVTDNFL 433
            :.|:|         |....|.|       :.|::|:||.:.:....|..||||..||.|...|..
Worm   188 RKIER---------PTEGKEGL-------VADLLWADPISGLSGFMNNQRGAGCGFGRDSVLNLC 236

  Fly   434 QRHRLSYVIRSHECKPNGHEFMHDNKIITIFSASNYYAIGSNKGAYIRLNNQLMPHF 490
            ...:|..|.|:|:...:|:||....|::|||||.:|.....|..|::..:.:|...|
Worm   237 SEFQLDLVCRAHQVVQDGYEFFAGRKLVTIFSAPHYCGQFDNCAAFMSCDEKLQCSF 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rdgC	NP_536738.3	IQ	89..111	CDD:197470
		MPP_RdgC	184..494	CDD:277364	104/317 (33%)
		EFh	616..681	CDD:238008
C47A4.3	NP_502650.1	MPP_superfamily	5..298	CDD:301300	103/313 (33%)
C47A4.3	NP_502650.1	PP2Ac	27..299	CDD:197547	97/287 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910