Protein Alignment rdgC and pef-1

DIOPT Version :10

• Sequence 1: NP_536738.3
• Gene: rdgC / 40224
• FlyBaseID: FBgn0265959
• Length: 746
• Species: Drosophila melanogaster
• Sequence 2: NP_741091.1
• Gene: pef-1 / 175257
• WormBaseID: WBGene00003969
• Length: 707
• Species: Caenorhabditis elegans
• Alignment Length: 707
• Identity: 282/707 - (39%)
• Similarity: 410/707 - (57%)
• Gaps: 51/707 - (7%)

  Fly    16 RRSSSVEDASSCRSSEIERVGASMQTLGPNGQPQSSAAQTSTRASSLLQLFQRRGWCKHFRKPLR 80
            |::.|.|...|.|::......:.......|.|..||::.....:||..:....:...|...|..|
 Worm     9 RQNPSTELKKSTRATTTTTSSSQRNNYNDNNQNTSSSSGNKKESSSSSKQHSSKKSKKSNSKKNR 73

  Fly    81 GMSASRAEKTIRAAIFIQKWYRRHQARREMQRRCNWQIFQNLEYASEQDQAELYKFFNDLIKHMP 145
            ..| .:.:.||::||.|||||||.:||.|.:||..||||..||||.||||.:||.||.|:|:.|.
 Worm    74 SPS-PQPQLTIKSAILIQKWYRRCEARLEARRRATWQIFTALEYAGEQDQLKLYDFFADVIRAMA 137

  Fly   146 QAAGRKNQYQG--SAHVSVLDD--KDDLVEEFGDIVNAKIE-------------------LPIRK 187
            :..|:.....|  |..:|.|..  |..|::..|:.|...:|                   ||:.|
 Worm   138 EENGKGGVENGRNSPLMSALSHYAKPSLMDSEGETVKKMLEDTSPTNVDIDRNYKGPTLSLPLDK 202

  Fly   188 NHIDLLIDVFRKKRGNRLHPKYVALILREAAKSLKQLPNISPVSTAVSQQVTVCGDLHGKLDDLL 252
            ..:..:|:.|  |....||||||.:||.||.|..|.:|::|.:||::|.|||:|||||||.|||.
 Worm   203 PQVAKMIEAF--KVNKVLHPKYVLMILHEARKIFKAMPSVSRISTSISNQVTICGDLHGKFDDLC 265

  Fly   253 VVLHKNGLPSSSNPYVFNGDFVDRGKRGLEVLLLLLSLYLAFPNAVFLNRGNHEDSVMNARYGFI 317
            ::|:|||.||..|||:|||||||||.:.:|||.:|.:|.:..|.:::||||||||.:||.|||||
 Worm   266 IILYKNGYPSVDNPYIFNGDFVDRGGQSIEVLCVLFALVIVDPMSIYLNRGNHEDHIMNLRYGFI 330

  Fly   318 REVESKYPRNHKRILAFIDEVYRWLPLGSVLNSRVLIVHGGFSDSTSLDLIKSIDRGKYVSILRP 382
            :|:.:||......|...:::|:.|||:.::::..:.:||||.||.|.:..:..|.|.::.|:|||
 Worm   331 KELSTKYKDLSTPITRLLEDVFSWLPIATIIDRDIFVVHGGISDQTEVSKLDKIPRHRFQSVLRP 395

  Fly   383 PLTDGEPLDK-------TEWQQIFDIMWSDPQATMGCVPNTLRGAGVWFGPDVTDNFLQRHRLSY 440
            |:..|...:|       .||:|:.|||||||:...||.||..||.|.:||.|:|.:||::|....
 Worm   396 PVNKGMESEKENSAVNVDEWKQMLDIMWSDPKQNKGCWPNVFRGGGSYFGADITASFLEKHGFRL 460

  Fly   441 VIRSHECKPNGHEFMHDNKIITIFSASNYYAIGSNKGAYIR-LNNQLMPHFVQYISAASQTKRLS 504
            ::||||||..|:||.|:|..:|:|||||||..|||:|||:: :.....||||||:  ||:|.|.|
 Worm   461 LVRSHECKFEGYEFSHNNTCLTVFSASNYYETGSNRGAYVKFIGKSKQPHFVQYM--ASKTHRKS 523

  Fly   505 -FKQRMGIVESSALKELAVRMRDHRDELEDEFRKYDPKDSGYISISHWCKVMENVTKLGLPWRLL 568
             .::|:|:||.||:|||..::.....:|:.||...|.:.||.:.|..|...:|.:|.|.|||..|
 Worm   524 TLRERLGVVEESAVKELKEKLSSFHTDLQKEFEIMDIEKSGKLPILKWSDCVERITGLNLPWIAL 588

  Fly   569 RDKLAP-GTDSQKVNYNRTLDLLDTDVILEAEADGMSVMDALYANKASLVAIFNIIDADNSGEIT 632
            ..|:|. ..|.:.|.|.....:.........|.|   ::::||.:|::|..:|..:|.||||:::
 Worm   589 APKVATLSEDGKYVMYKEDRRIAQVGGTHAQEKD---IVESLYRHKSTLETLFRFMDKDNSGQVS 650

  Fly   633 LDEFETAIDLLVAHMPGAYSKAEM-----LEKCRMMDLNGDGKVDLNEFLEAFRLSD 684
            :.||..|.::|     |.|:|..:     .:....:|.|.||.:||||.||||||.|
 Worm   651 MKEFIDACEVL-----GKYTKRPLQTDYISQIAESIDFNKDGFIDLNELLEAFRLVD 702

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rdgC	NP_536738.3	IQ	89..111	CDD:197470	14/21 (67%)
		MPP_RdgC	184..494	CDD:277364	152/317 (48%)
		FRQ1	527..681	CDD:444056	50/159 (31%)
		EFh	616..681	CDD:238008	25/69 (36%)
pef-1	NP_741091.1	MPP_RdgC	199..515	CDD:277364	152/317 (48%)
		EFh	634..699	CDD:238008	25/69 (36%)