DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rdgC and F58G1.3

DIOPT Version :9

Sequence 1:	NP_536738.3	Gene:	rdgC / 40224	FlyBaseID:	FBgn0265959	Length:	746	Species:	Drosophila melanogaster
Sequence 2:	NP_496754.2	Gene:	F58G1.3 / 174933	WormBaseID:	WBGene00010265	Length:	364	Species:	Caenorhabditis elegans

Alignment Length:	375	Identity:	101/375 - (26%)
Similarity:	162/375 - (43%)	Gaps:	78/375 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   131 AELYKFFNDLIKHMPQAAGRKNQYQGSAHVSVLDDKDDLVEEFGDIVNAKIELPIRKNHIDLLID 195
            :|:.||  ||.|..|:.|               :..||.::....:            :.|..|:
Worm    19 SEISKF--DLAKENPRLA---------------EWMDDCIKRMNSL------------YKDTNIN 54

  Fly   196 VFRKKRGNRLHPKYVALILREAAKSLKQLPNISPVSTAVSQQVTVCGDLHGKLDDLLVVLHKNG- 259
            :.....|:.     :..|:|..........|:......:.    |.||:|.:..|:..:....|
Worm    55 ICNVMTGHE-----IIAIIRMVEAIFMDESNLCEAEAPIK----VIGDIHAQFQDMNRLFDLIGR 110

  Fly   260 LPSSSNPYVFNGDFVDRGKRGLEVLLLLLSLYLAFPNAVFLNRGNHEDSVMNARYGFIREVESKY 324
            :|...  .:|.||:||||.:|:|||:||..|.:.:.:.::|.|||||...:|..|||..|.:.||
Worm   111 VPEEK--LMFLGDYVDRGPQGIEVLILLFCLKIRYRDRIYLLRGNHETPSVNKIYGFYVECQYKY 173

  Fly   325 PRNHKRILAFIDEVYRW---------LPLGSVLNSRVLIVHGGFS-DSTSLDLIKSIDRGKYVSI 379
                        .|..|         :|:..:::.|||.:|||.| :..:||.|::|.|
Worm   174 ------------GVGLWWDFQTCFNRMPMSGLISKRVLCMHGGLSPELINLDTIRNIPR------ 220

  Fly   380 LRPPLTDGEPLDKTEWQQIFDIMWSDPQATMGCVPNTLRGAGVWFGPDVTDNFLQRHRLSYVIRS 444
               |.   ||||:   ..:.|::||||........:::||....||..|.:...:...:..:||.
Worm   221 ---PC---EPLDR---GLLIDLLWSDPTNKGEGWFHSIRGISYMFGKGVVEQACKSLEIDLIIRG 276

  Fly   445 HECKPNGHEFMHDNKIITIFSASNYYAIGSNKGAYIRLNNQLMPHFVQYI 494
            |:...:|:|.|...::||:||..||.|..:|..|.:.||..|...|.|.|
Worm   277 HQVVQDGYEMMAGRRLITVFSVPNYCAQFTNAAAVVCLNANLQVSFQQLI 326

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rdgC	NP_536738.3	IQ	89..111	CDD:197470
		MPP_RdgC	184..494	CDD:277364	90/320 (28%)
		EFh	616..681	CDD:238008
F58G1.3	NP_496754.2	MPP_superfamily	37..327	CDD:301300	93/340 (27%)
F58G1.3	NP_496754.2	PP2Ac	59..329	CDD:197547	89/306 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000