DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rdgC and F52H3.6

DIOPT Version :9

Sequence 1:	NP_536738.3	Gene:	rdgC / 40224	FlyBaseID:	FBgn0265959	Length:	746	Species:	Drosophila melanogaster
Sequence 2:	NP_496167.1	Gene:	F52H3.6 / 174561	WormBaseID:	WBGene00009948	Length:	329	Species:	Caenorhabditis elegans

Alignment Length:	359	Identity:	99/359 - (27%)
Similarity:	170/359 - (47%)	Gaps:	55/359 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   168 DLVEEFGDIVNAKIELPIRKNHIDLLIDVFRKKRGNRLHPKYVALILREAAKSLKQLPNISPVST 232
            |.:....|..|..:...|.:..||::|:            |...::|.:|.....|.|
Worm     9 DRLLSVNDTSNPSLTRCINEADIDVVIE------------KCTKILLAQATMVEVQAP------- 54

  Fly   233 AVSQQVTVCGDLHGKLDDLLVVLHKNGLPSSSNPYVFNGDFVDRGKRGLEVLLLLLSLYLAFPNA 297
                 :.||||:||:..|||.:.::...|...| |:|.||:||||::.|||:.||::..:.:||.
Worm    55 -----IAVCGDIHGQYTDLLRIFNRCSFPPDQN-YLFLGDYVDRGRQQLEVICLLMAYKIRYPNR 113

  Fly   298 VFLNRGNHEDSVMNARYGFIREVESKYPRNHKRILAFIDE---VYRWLPLGSVLNSRVLIVHGGF 359
            .|:.|||||.:.:|..|||..|.:.:|.      ||..::   ::..|||.::::.|:..:|||.
Worm   114 FFILRGNHECASINRTYGFYDECKRRYS------LALYNDFQNLFNHLPLCAMISGRIFCMHGGL 172

  Fly   360 SDSTSLDLIKSIDRGKYVSILRPPLTDGEPLDKTEWQQIFDIMWSDPQATMGCVPNTLRGAGVWF 424
            |.       |.:...:...|.|       |.|........|::|:||:..|.....:.||....|
Worm   173 SQ-------KLVSWTQLAEITR-------PFDPPNNSLAMDLLWADPENNMTGWAESSRGVSQIF 223

  Fly   425 GPDVTDNFLQRHRLSYVIRSHECKPNGHEFMHDNKIITIFSASNYYAIGSNKGAYIRLNNQLMPH 489
            |.||..:|.::..:..:.|.|:...:|:||..|.:::|||||..|.....|..|.:.::.:|:..
Worm   224 GADVVKDFTEKMNIDLIARGHQVVQDGYEFFADKRLVTIFSAPKYCGEFDNNAAVMIVDERLIVS 288

  Fly   490 FVQYISAASQTKRLSFKQRMGIVESSALKELAVR 523
            | :.:..|.:..::   |..|   ::|.|.::.|
Worm   289 F-EILKPAIREVKI---QARG---AAAAKNMSTR 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rdgC	NP_536738.3	IQ	89..111	CDD:197470
		MPP_RdgC	184..494	CDD:277364	90/312 (29%)
		EFh	616..681	CDD:238008
F52H3.6	NP_496167.1	MPP_superfamily	3..294	CDD:301300	93/330 (28%)
F52H3.6	NP_496167.1	PP2Ac	26..295	CDD:197547	90/314 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910