Protein Alignment Clc and CLC1

DIOPT Version :9

• Sequence 1: NP_001163480.1
• Gene: Clc / 40221
• FlyBaseID: FBgn0024814
• Length: 219
• Species: Drosophila melanogaster
• Sequence 2: NP_011683.3
• Gene: CLC1 / 853077
• SGDID: S000003399
• Length: 233
• Species: Saccharomyces cerevisiae
• Alignment Length: 230
• Identity: 59/230 - (25%)
• Similarity: 95/230 - (41%)
• Gaps: 40/230 - (17%)

  Fly     6 DFAAKEDVDPAAEFLAREQSALGD---------LEAEITGGSASAPPAASTDEGLGELLGGTASE 61
            ||...:..|...:||.||...|||         ||.|       |.||...|    |:.......
Yeast    14 DFTPNDKKDDDTDFLKREAEILGDEFKTEQDDILETE-------ASPAKDDD----EIRDFEEQF 67

  Fly    62 GDLLSAGGTGGLESSTGSFEVIGGESN----------EPVGISGPPPSREEPEKIRKWREEQKQR 116
            .|:.||.|....:.: ||..|..|..|          |....|......:..|.:.:|::.:...
Yeast    68 PDINSANGAVSSDQN-GSATVSSGNDNGEADDDFSTFEGANQSTESVKEDRSEVVDQWKQRRAVE 131

  Fly   117 LEEKDIEEERKKEELRQQSKKELDDWLRQIGESISKTKL-----ASRNAEKQAATLENGTIEPGT 176
            :.|||:::|..|:||:.::.|.:||:.    :|.:|.|.     |::.||......:....:..|
Yeast   132 IHEKDLKDEELKKELQDEAIKHIDDFY----DSYNKKKEQQLEDAAKEAEAFLKKRDEFFGQDNT 192

  Fly   177 EWERIAKLCDFNPKVNKAGKDVSRMRSIYLHLKQN 211
            .|:|..:|.:.:......|:|.|:::.|.|.||.|
Yeast   193 TWDRALQLINQDDADIIGGRDRSKLKEILLRLKGN 227

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Clc	NP_001163480.1	Clathrin_lg_ch	6..212	CDD:279433	59/230 (26%)
CLC1	NP_011683.3	Clathrin_lg_ch	1..227	CDD:395863	58/228 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4031
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002725
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_103026
Panther	1	1.100	-	-	LDO	PTHR10639
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R206
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.840