DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Clc and AT2G20760

DIOPT Version :9

Sequence 1:	NP_001163480.1	Gene:	Clc / 40221	FlyBaseID:	FBgn0024814	Length:	219	Species:	Drosophila melanogaster
Sequence 2:	NP_565484.1	Gene:	AT2G20760 / 816605	AraportID:	AT2G20760	Length:	338	Species:	Arabidopsis thaliana

Alignment Length:	259	Identity:	72/259 - (27%)
Similarity:	99/259 - (38%)	Gaps:	87/259 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 DDFAAKEDVDPAAEFLAREQSALGDLEAEITGG--SASAPPAASTDEGLGELLGGTAS------- 60
            :||...::...|.:...:.||          ||  |.:..||:....|.|      ||
plant    20 EDFGGYDNFSEAQQPPTQHQS----------GGFSSFNGDPASPNGYGFG------ASSPNHDFS 68

  Fly    61 ---EGDLLSAGGTGGLESSTGSFEVIGGE----SNEPVGISGPPPSREEPEKIRKWREEQKQRLE 118
               |..:..|.|.||     ||    ||:    |:.|: :..|...|||..:.|:||......||
plant    69 SPFESSVNDANGNGG-----GS----GGDAIFASDGPI-LPDPNEMREEGFQRREWRRLNTIHLE 123

  Fly   119 EKDIEEERKKEELRQQSKKELDDWLRQIGESISKT------------KLASRNAEKQAATLENGT 171
            ||    |:|::|:|.|...|.:|:.:...|...||            ||...|.||....::.
plant   124 EK----EKKEKEMRNQIITEAEDFKKAFYEKRDKTIETNKTDNREKEKLYWANQEKFHKEVDK-- 182

  Fly   172 IEPGTEWERIAKLC----------------DFNPKVN-----KAGK--DVSRMRSIYLHLKQNP 212
                ..|:.||:|.                |..|.||     |.||  |:.|||.|:|.||.||
plant   183 ----HYWKAIAELIPREVPNIEKKRGKKDPDKKPSVNVIQGPKPGKPTDLGRMRQIFLKLKTNP 242

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Clc	NP_001163480.1	Clathrin_lg_ch	6..212	CDD:279433	70/256 (27%)
AT2G20760	NP_565484.1	motB	<253..>334	CDD:235665
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR10639
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	2	2.060