Protein Alignment Clc and clta

DIOPT Version :9

• Sequence 1: NP_001163480.1
• Gene: Clc / 40221
• FlyBaseID: FBgn0024814
• Length: 219
• Species: Drosophila melanogaster
• Sequence 2: XP_012813602.1
• Gene: clta / 394591
• XenbaseID: XB-GENE-944169
• Length: 233
• Species: Xenopus tropicalis
• Alignment Length: 247
• Identity: 86/247 - (34%)
• Similarity: 121/247 - (48%)
• Gaps: 63/247 - (25%)

  Fly     4 GDDFAAKEDVDPAAEFLAREQSALGDLEAEITGGSASAPPAASTDEGLGELLGGTASEGDLLSAG 68
            |:..:|:|  ||||.|||:::|.:..:|               .|||...|..|   |..:....
 Frog    11 GNGVSAEE--DPAAAFLAQQESEIAGIE---------------NDEGFSILDSG---EVPMSLQA 55

  Fly    69 GTGGLESSTGSFEVIGG----ESNEP----VGISGPPPSREEPEKIRKWREEQKQRLEEKDIEEE 125
            |.|..::      |:.|    |:|.|    ..||.....:.|||.||||||||:.|||..|...:
 Frog    56 GDGATDT------VMNGDFYQETNGPTDGYAAISHADRLQAEPESIRKWREEQRSRLEMLDANSK 114

  Fly   126 RKKEELRQQSKKELDDWLRQIGESISKTKLASRNAE----KQ---------------AATLENGT 171
            :::.|.:.::.|||::|..:..|.:.|||..:|.|:    ||               ..:||...
 Frog   115 KQETEWKDKAGKELEEWYARQDELLQKTKANNRVADEAFYKQPFADVIGYVTNINHPCYSLEQAA 179

  Fly   172 IE----------PGTEWERIAKLCDFNPKVNKAGKDVSRMRSIYLHLKQNPI 213
            .|          |||||||:|:|||||||.:|..||||||||:.:.|||.|:
 Frog   180 EEAFVSDVEETSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLISLKQAPL 231

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Clc	NP_001163480.1	Clathrin_lg_ch	6..212	CDD:279433	84/242 (35%)
clta	XP_012813602.1	Clathrin_lg_ch	10..228	CDD:366457	83/242 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	132	1.000	Domainoid score	I5064
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H1384
Inparanoid	1	1.050	133	1.000	Inparanoid score	I4478
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1577821at2759
OrthoFinder	1	1.000	-	-		FOG0002725
OrthoInspector	1	1.000	-	-		otm48022
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R206
SonicParanoid	1	1.000	-	-		X3012
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.090